New antiviral strategy targets host cell structures to combat HSV-1 Researchers are exploring a novel class of antivirals that go beyond directly attacking viruses. Pin1 inhibitors, a group of compounds that modulate the host enzyme peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1), have shown promise in curbing herpes simplex virus 1 (HSV-1) replication. HSV-1 is the…