Tag: tumor heterogeneity
-
CTHRC1-driven Breast Cancer Progression: Palmitoylation Networks and Spatial Heterogeneity
Overview: Unraveling CTHRC1’s Role in Breast Cancer Breast cancer remains the most common malignancy affecting women worldwide, demanding deeper insights into its molecular drivers. Among emerging players, CTHRC1 has gained attention for its potential to modulate tumor progression through diverse signaling circuits. This article synthesizes current knowledge on how CTHRC1 influences breast cancer dynamics, with…
-
CTHRC1-driven breast cancer progression: palmitoylation networks and spatial heterogeneity
Understanding CTHRC1 in breast cancer progression Breast cancer remains the leading malignancy among women worldwide, driving urgent research into its molecular underpinnings and how these insights can translate into better diagnostics and therapies. Among the emerging molecular players, CTHRC1 (Collagen Triple Helix Repeat Containing 1) has attracted attention for its potential role in promoting tumor…
-
Single-Chromosome Sequencing in Human Cancers: A Window into Gene-Specific Tumor Biology
Introduction: Why Focus on a Single Chromosome? Cancer genetics has traditionally relied on bulk genome analyses, which average signals across millions of cells. While informative, this approach can obscure rare but functionally critical events occurring on individual chromosomes. The idea of single-chromosome sequencing—an approach that isolates and analyzes one chromosome at a time—offers a rare…