Tag: Treatment Resistance
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Understanding the Role of Highly Plastic Cancer Cells in Progression and Drug Resistance
What Does Cell Plasticity Mean for Cancer? Cancer is not a uniform mass of identical cells. Within tumors, a small but potent subpopulation exhibits high plasticity—the ability to alter their identity, traits, and behavior in response to their environment. This plasticity allows cancer cells to switch between states that promote growth, invasion, and survival, including…
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Targeting Highly Plastic Cancer Cells: A Path to Slower Progression and Better Therapies
Introduction: The Challenge of Cancer Cell Plasticity Cancer is not a uniform mass of identical cells. It is a dynamic ecosystem where a small subpopulation can adapt, change identities, and drive disease progression. Emerging research highlights the role of highly plastic cancer cells—cells that can shift their behavior and characteristics in response to environmental pressures,…
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Targeting Highly Plastic Cancer Cells: A New Frontier in Combating Progression and Drug Resistance
Understanding cancer cell plasticity Cancer is not a uniform mass of identical cells. Within a tumor, a small subpopulation of cells can exhibit remarkable plasticity—the ability to change their identity and behavior in response to environmental cues. This cellular flexibility enables tumors to adapt, survive, and evolve under therapeutic pressure. Recent research highlights that these…
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HIV Strains in India: Resistance to Broadly Neutralising Antibodies
Introduction In recent years, the HIV landscape has evolved significantly, particularly in regions like India. A notable study published in Science in 1994 introduced the broadly neutralising antibody (bNAb) known as b12, which showcased the potential of antibodies to neutralise HIV effectively. However, emerging evidence suggests that certain strains of HIV in India have developed…