Tag: tissue repair


  • Checkpoint inhibitors reveal tissue repair role, offering hope for chronic wounds

    Checkpoint inhibitors reveal tissue repair role, offering hope for chronic wounds

    Unveiling a new function for a familiar immune brake Checkpoint inhibitors are well known for their role in cancer therapy, where they release the immune system’s brakes to attack tumor cells. In a surprising twist, researchers from the University of Zurich (UZH) have uncovered a second, equally important function: TIGIT, a checkpoint protein, promotes tissue…

  • Checkpoint Inhibitor TIGIT Promotes Tissue Repair

    Checkpoint Inhibitor TIGIT Promotes Tissue Repair

    New role for checkpoint inhibitors in tissue healing Checkpoint inhibitors are best known for unleashing the immune system against cancer. A surprising new perspective emerging from researchers at the University of Zurich (UZH) shows that one of these inhibitors, TIGIT, also plays a vital part in tissue repair. Published in Nature Immunology, the study reveals…

  • Checkpoint inhibitors aid tissue repair, offering new hope for chronic wounds

    Checkpoint inhibitors aid tissue repair, offering new hope for chronic wounds

    Summary: A new role for checkpoint inhibitors in tissue repair Checkpoint inhibitors, best known for unleashing the immune system against cancer, may also help heal damaged tissues. Researchers at the University of Zurich (UZH) have identified a previously unknown function of one such inhibitor, TIGIT: it promotes tissue repair after viral infection. The discovery, published…

  • TIGIT Immune Checkpoint Promotes Tissue Healing and Regeneration

    TIGIT Immune Checkpoint Promotes Tissue Healing and Regeneration

    Overview: A new role for an immune checkpoint Immune checkpoint inhibitors have transformed cancer therapy by releasing the brakes on the immune system. A surprising new finding from researchers at the University of Zurich (UZH) reveals that one such brake, TIGIT, does more than help tumor-fighting immune cells—it also promotes tissue healing. This discovery could…

  • Planarian stem cells defy niche signals, unlocking the secrets of regeneration

    Planarian stem cells defy niche signals, unlocking the secrets of regeneration

    Planarian stem cells reveal a new horizon in tissue regeneration Planarian flatworms have long fascinated scientists with their extraordinary regenerative powers. A new study from the Stowers Institute for Medical Research, published in Cell Reports, shows that planarian stem cells may not rely on a local niche in the way many other organisms do. Instead,…