Tag: Therapeutics
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A Safer Way to Make Cells Burn More Calories: A Breakthrough in Metabolism
New Hope in the Battle Against Obesity Obesity remains a global health challenge, linked to diabetes, heart disease, and certain cancers. For years, researchers have pursued methods to raise the body’s energy expenditure—how many calories our cells burn—without relying on injections or risky drugs. A recent breakthrough suggests a safer approach to tipping the metabolic…
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Scientists Unveil a Safer Way to Make Cells Burn More Calories
A Rising Challenge: Obesity and the Search for Safer Solutions Obesity affects millions worldwide, increasing the risk of diabetes, heart disease, and certain cancers. For years, researchers have pursued treatments that boost how efficiently our bodies burn calories. Many currently available options rely on injections or medications with side effects that make long-term use challenging.…
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Tiger BioSciences Highlights 2025 Clinical Milestones After Bold Research Investment
Overview: A Year of Strategic Investment and Impact In 2025, Tiger BioSciences positioned itself at the forefront of evidence-based biotherapeutics, translating a significant investment in scientific research into tangible clinical milestones. The company’s renewed emphasis on rigorous preclinical validation, translational science, and disciplined trial design aimed to accelerate the journey from discovery to patient impact.…
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Scientists Pinpoint Brain Cells That Drive Anxiety in Mice
Overview: A breakthrough in the anxiety puzzle Anxiety disorders affect millions and remain one of the most common mental health challenges in the United States. While therapies and medications help many, scientists have long sought to understand the cellular roots of anxiety. A new study in mice provides a sharper map of the brain cells…
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Astrocyte-Driven Reversal of Alzheimer’s Cognitive Decline: Mouse Study Sparks Hope
Groundbreaking Astrocyte Findings Point to a Natural Brain Cleanup Mechanism A recent study from Baylor College of Medicine highlights a promising, naturally occurring brain process that helps clear amyloid plaques and maintain cognitive function in mouse models of Alzheimer’s disease. The research focuses on astrocytes, star-shaped support cells in the brain, and how they can…
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CTHRC1-driven breast cancer progression: palmitoylation networks and spatial heterogeneity
Understanding CTHRC1 in breast cancer progression Breast cancer remains the leading malignancy among women worldwide, driving urgent research into its molecular underpinnings and how these insights can translate into better diagnostics and therapies. Among the emerging molecular players, CTHRC1 (Collagen Triple Helix Repeat Containing 1) has attracted attention for its potential role in promoting tumor…
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Aging Spleen Shapes T Cell Health: New Study Reveals Mechanism and Therapies
Understanding the aging immune system As people age, the immune system often becomes less effective, leaving older adults more susceptible to infections and slower to recover. A recent study from the Technion—Israel Institute of Technology Faculty of Biology sheds light on a specific cofactor in this decline: the aging spleen. The researchers describe how changes…
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Research Uncovers Inflammasome’s Role in Male Periodontitis
New Findings Link Inflammasome to Male Periodontitis A recent study from the University of North Carolina at Chapel Hill shines new light on the inflammatory processes behind periodontitis, a leading cause of tooth loss worldwide. The UNC Adams School of Dentistry research identifies a key role for the inflammasome—a multiprotein complex inside immune cells—in driving…
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LassoESM: A New AI-Driven Path to Therapeutic Lasso Peptides
Revealing a new AI tool for lasso peptides In the race to develop novel therapeutics for cancer and infectious diseases, lasso peptides have emerged as a promising class. Their knot-like structures confer remarkable stability and diverse biological activities, making them attractive candidates for future drugs. A collaboration led by the Carl R. Woese Institute for…
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LassoESM: A New AI Tool Accelerating Therapeutic Lasso Peptide Discovery
AI Meets Molecular Biology: The Rise of LassoESM In the race to uncover new therapeutics for cancer and infectious diseases, lasso peptides stand out for their knot-like, highly stable structures and diverse biological activities. A collaboration led by researchers at the Carl R. Woese Institute for Genomic Biology has given the field a powerful new…