Tag: therapeutic targets
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Scientists Identify Brain Cells That Drive—and Suppress—Anxiety in Mice
New insights into the neural roots of anxiety Anxiety disorders affect roughly 20% of adults in the United States at some point in their lives, making them among the most common mental health conditions. While clinical therapies help many, the underlying biology of anxiety has remained complex and only partly understood. Recent research in mice…
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Improving Brain Resilience: Rab Proteins and Future Treatments
How Rab Proteins Orchestrate Synaptic Potentiation Memory formation hinges on synaptic potentiation—the strengthening of connections between neurons. This growth is driven by a tightly coordinated delivery system within neurons that supplies the building blocks essential for remodeling synapses. A large family of cellular switches, known as Rab proteins, governs the flow of these supplies, directing…
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UChicago Scientists Link CPD Gene Mutation to Deafness and Point to Treatments
New discovery ties CPD gene mutations to a rare form of congenital deafness A collaborative international team of researchers has uncovered a gene mutation in CPD that plays a pivotal role in a rare form of congenital hearing loss. The study, led by scientists from the University of Chicago and the University of Miami, with…
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Mitochondrial DNA Shortfalls May Fuel Inflammation as We Age
New Clues on Inflammation and Aging: Mitochondrial DNA’s Role Scientists are uncovering a surprising link between the tiny powerhouses inside our cells and the chronic inflammation often seen as we grow older. A study led by researchers at the Max Planck Institute for Biology of Ageing in Germany suggests that when mitochondria struggle to replicate…