Tag: TB treatment
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Economic and Clinical Burdens of Tuberculosis Treatment in Vulnerable Patients
Introduction Tuberculosis (TB) remains a major global health challenge, disproportionately affecting vulnerable populations. While the disease itself poses severe health risks, the economic and clinical burdens of TB treatment can be equally daunting for patients who already face social, financial, and medical barriers. This article examines how financial costs, health system gaps, and patient-specific vulnerabilities…
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High-Dose Rifampin Shows No Advantage for Tuberculosis Meningitis, Study Finds
Background: Rethinking Rifampin Dosing in TB Meningitis Tuberculosis meningitis (TBM) is a severe form of TB that affects the brain and central nervous system. Clinicians have debated whether increasing the dose of rifampin, a cornerstone anti-TB drug, could improve drug penetration into the cerebrospinal fluid and, in turn, patient outcomes. Earlier small studies and theoretical…
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Targeted Steroid Use Shows Promise Against Tuberculosis
New findings open doors for adjunctive steroid therapy in TB care Tuberculosis (TB) remains a global health challenge, affecting more than 10 million people each year. A new study published in Scientific Reports suggests that carefully targeted use of steroids could serve as a universal complementary treatment to bolster the body’s defense against TB while…
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Targeted Steroid Use Could Complement TB Treatment by Boosting Macrophage Defense
Overview: Rethinking Steroids in TB care Tuberculosis (TB) remains a global health challenge, infecting more than 10 million people annually and claiming around 1.25 million lives each year. While corticosteroids like dexamethasone are used in select TB scenarios, notably TB meningitis, their broader impact on immune cells—especially lung macrophages—has been unclear. A new study from…