Tag: tau protein
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Tau Fibril Formation Boosted by Polymer Physics Insights
Introducing a fresh lens on Alzheimer’s pathology In a groundbreaking cross-disciplinary venture, researchers from Tokyo Metropolitan University have adapted concepts from polymer physics to shed new light on the tau protein fibril formation that characterizes a key pathology in Alzheimer’s disease. By borrowing ideas about how polymers behave at the mesoscopic scale, the team aims…
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Polymer Physics Illuminates Tau Fibril Formation in Alzheimer’s Disease
Unlocking a Key Alzheimer’s Pathology with Polymer Physics Researchers from Tokyo Metropolitan University are applying concepts from polymer physics to unravel a central mystery of Alzheimer’s disease: how tau proteins assemble into the fibrillar structures that destabilize neurons. By treating tau aggregates as dynamic, filament-forming polymers, the team aims to map the steps that precede…
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Polymer Physics Sheds Light on Tau Fibril Formation in Alzheimer’s
New Cross-Disciplinary Insight into Alzheimer’s Pathology Researchers at Tokyo Metropolitan University have bridged fields by applying concepts from polymer physics to the study of tau protein fibrillogenesis, a central feature of Alzheimer’s disease pathology. By treating tau proteins as dynamic polymers that can assemble, rearrange, and crystallize under cellular conditions, the team is uncovering the…
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New MRI Findings on Brain Shape Shifts and Dementia Risk
Overview of the study A recent study published in Nature Communications sheds new light on how the aging brain changes beyond the loss of tissue. Rather than focusing solely on how much tissue shrinks in specific regions, researchers analyzed the brain’s overall shape as revealed by magnetic resonance imaging (MRI). The work examined more than…
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Brain shape changes linked to dementia: MRI findings
Brain shape changes as a potential early signal for dementia A new study published in Nature Communications on September 29 reveals that the aging brain’s shape, not just its tissue loss, shifts in systematic ways that correlate with cognitive function. The research suggests that magnetic resonance imaging (MRI) can capture these geometric changes, which may…