Tag: tau
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CUL5: The Brain’s Garbage Collector That Clears Toxic Tau and Shields Neurons
New Discovery: A Brain Cleanup Crew Called CUL5 Scientists at the University of California, San Francisco, have identified a cellular mechanism that acts like a waste collector in the brain. The protein CUL5 appears to help neurons dispose of toxic tau clumps, which are a hallmark of several neurodegenerative diseases and a major driver of…
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Brain Guardian: How CUL5 Clears Tau Clumps to Protect Neurons
Overview: A New Player in the Brain’s Waste Management In a landmark study from UC San Francisco, scientists have identified a crucial cellular picker-upper in the brain—CUL5—that helps clear toxic tau clumps. These clumps are notorious for driving neurodegenerative diseases and dementia. By acting as a molecular garbage collector, higher levels of CUL5 in neurons…
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Against All Odds: The Doug Whitney Story of Unexpected Alzheimer’s Resilience
Against All Odds: A Man Who Defies a Grim Genetic Forecast Doug Whitney, a 76-year-old retiree from Seattle, carries a genetic mutation historically tied to early-onset Alzheimer’s disease. Yet decades after doctors predicted a cognitive decline would begin in his 40s or 50s, he remains mentally sharp and engaged with family, friends, and science. His…