Tag: targeted therapy
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Blocking PDIA1 and PDIA5: A New Strategy to Weaken Prostate Tumors and Boost Drug Effectiveness
New vulnerability in prostate cancer identified: two enzymes that protect the androgen receptor A major international study has uncovered a promising vulnerability in prostate cancer cells that could improve treatment for one of the most common cancers in men. Published in the Proceedings of the National Academy of Sciences (PNAS), the research shows that two…
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Blocking two enzymes weakens prostate tumors and boosts drug effectiveness
New vulnerability uncovered in prostate cancer: targeting PDIA1 and PDIA5 A major international study has identified a promising vulnerability in prostate cancer cells that could improve how this common male cancer is treated. Published in the Proceedings of the National Academy of Sciences (PNAS), researchers from Flinders University in Australia and the South China University…
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Genetic Link to Osteosarcoma Found: SMARCAL1 Gene Inheritance Raises Risk in Children
Breakthrough in Pediatric Cancer Genetics A collaborative study led by researchers at Cleveland Clinic Children’s has identified an inherited genetic factor that may elevate the risk of osteosarcoma, the most common malignant bone tumor in children and young adults. Published in the Journal of Clinical Oncology, the work analyzed genetic data from thousands of cancer…
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New Compound Shows Promise in Blocking Lung Cancer Growth
A Promising Breakthrough in Lung Cancer Treatment Researchers are reporting a promising advance in the fight against lung cancer: a novel small-molecule compound that effectively blocks the growth of cancer cells in preclinical studies. The compound targets a key signaling axis that many lung tumors rely on to proliferate and evade cell death. In laboratory…