Tag: systematic review
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Can Vitamin D Supplementation Influence Cardiometabolic Health in Overweight and Obese Children and Adolescents? A Grade-Assessed Systematic Review and Meta-Analysis of Randomized Trials
Overview Overweight and obesity in children and adolescents are pressing global health concerns linked to adverse cardiometabolic outcomes. Questions remain about whether vitamin D supplementation can modulate cardiometabolic risk factors such as insulin resistance, lipid profiles, blood pressure, and inflammatory markers in this population. This article summarizes a grade-assessed systematic review and meta-analysis of randomized…
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Vitamin D Supplementation and Cardiometabolic Health in Overweight Children and Adolescents: A Systematic Review and Meta-analysis
Overview Overweight and obesity in children and adolescents are linked to adverse cardiometabolic outcomes, including insulin resistance, dyslipidemia, hypertension, and early atherosclerotic changes. Vitamin D has attracted interest as a potential modulator of metabolic health due to its roles in inflammation, glucose metabolism, and endothelial function. This article summarizes a grade-assessed systematic review and meta-analysis…
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Melatonin and ART Outcomes: Systematic Review
Introduction Melatonin (MT) is recognized for its role in regulating circadian rhythms and protecting cells from oxidative stress. Growing evidence suggests that MT may influence reproductive biology by improving oocyte quality, reducing oxidative damage, and potentially enhancing endometrial receptivity. This has spurred a wave of randomized and non-randomized studies examining MT as an adjunct to…
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Melatonin Supplementation and ART Outcomes: A Systematic Review and Meta-Analysis
Introduction Melatonin (MT) is more than a sleep hormone. It plays a multifaceted role in reproductive biology, influencing oocyte quality, embryo development, and endometrial receptivity. With infertility affecting millions worldwide, researchers have explored MT supplementation as a potential adjunct to assisted reproductive technology (ART) protocols. This article synthesizes current evidence from randomized trials and observational…
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Melatonin Supplementation and ART Outcomes: Insights from a Systematic Review and Meta-Analysis
Overview: Melatonin in Reproductive Medicine Melatonin (MT) is best known for its role in regulating circadian rhythms, but it also plays a part in reproductive biology. Growing interest in MT supplementation stems from its antioxidant, anti-inflammatory, and mitochondrial-supporting properties, which may influence oocyte quality, embryo development, and implantation processes. As assisted reproductive technology (ART) expands…
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Prevalence of psychiatric disorders among Nigerians with neurological conditions: a systematic review
Overview This systematic review, conducted in Nigeria, evaluates how common mental disorders are among people living with neurologic conditions. Following established methodological guidelines from PRISMA and the Joanna Briggs Institute, the study synthesizes data from 18 Nigerian studies (2010–2024) involving 4,457 participants across eight states. The focus is on disorders diagnosed by clinicians or identified…
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Prevalence of mental disorders among people with neurologic conditions in Nigeria: a systematic review
Introduction Mental health and neurology intersect in ways that matter for patient outcomes and healthcare planning. This systematic review synthesizes evidence on the prevalence of mental disorders among people with neurologic conditions in Nigeria, following established guidelines (PRISMA and JBI). The study maps how common psychiatric comorbidities are in stroke survivors, people with epilepsy, and…
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Socioeconomic Factors, Parental Awareness, and HPV Vaccination Acceptability in Sub-Saharan Africa: A Systematic Review
Overview Human papillomavirus (HPV) vaccination is a cornerstone of cervical cancer prevention. In Sub-Saharan Africa (SSA), cervical cancer remains a leading cause of death among women, and national HPV vaccination programs are unevenly implemented across countries. A recent systematic review and meta-analysis synthesized evidence on how parental socioeconomic factors influence awareness and acceptability of HPV…
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Socioeconomic Factors and Parental Awareness and Acceptance of HPV Vaccination in Sub-Saharan Africa: A Systematic Review and Meta-Analysis
Overview Human papillomavirus (HPV) can lead to cervical cancer and other diseases, with Africa bearing a significant share of the global burden. In sub-Saharan Africa (SSA), vaccination programs have expanded in recent years, but parental awareness and acceptance remain uneven. This systematic review and meta-analysis synthesize evidence on how socioeconomic factors—education, income, occupation, and urban…
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Chronic Urticaria Treatments: Patient Preferences & Choices
Understanding What Matters to Patients with Chronic Urticaria Chronic urticaria, characterized by persistent hives, itching, and swelling, can profoundly disrupt daily life. A recent systematic review of 18 studies involving more than 28,000 participants highlights what patients and caregivers value most when choosing treatments. While efficacy is essential, how a treatment aligns with patients’ preferences…