Tag: synaptic vesicles
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Cryo-ET Uncovers Kiss-Shrink-Run: A Hybrid Mechanism for Synaptic Vesicle Exocytosis
Breaking the old dichotomy in neurotransmission For decades, neuroscientists debated whether synaptic vesicles released neurotransmitters through a fleeting “kiss-and-run” event or an irreversible “full collapse” into the presynaptic membrane. A pioneering study from the University of Science and Technology of China (USTC) now reveals a nuanced third act—one that reconciles two long-standing models by showing…
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Cryo-ET Unveils Kiss-Shrink-Run: A Hybrid Model of Neurotransmitter Release
Cracking the Code of Neurotransmission The brain’s ability to transmit signals rapidly hinges on the precise choreography of synaptic vesicle exocytosis. For decades, scientists debated whether vesicles simply “kiss” the presynaptic membrane and retreat (kiss-and-run) or fully collapse to release their neurotransmitters. A groundbreaking study from the University of Science and Technology of China (USTC),…
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Kiss-Shrink-Run: A Hybrid Mechanism Unveiled for Neuronal Release
Cracking the Code of Neurotransmission The brain’s ability to communicate with astonishing speed hinges on how synaptic vesicles release their chemical messages. For decades, scientists debated whether vesicles briefly touched the presynaptic membrane in a “kiss-and-run” fashion or fully merged in an irreversible “full collapse.” A groundbreaking study from the University of Science and Technology…