Tag: spatial transcriptomics
-
First Brain Cell Atlas: Clues to Neurodevelopmental and Psychiatric Disorders
What is a Brain Cell Atlas? The Brain Cell Atlas is a comprehensive roadmap of the brain’s cellular landscape. By cataloging the diverse types of brain cells, their gene activity, and how they interact across different regions and developmental stages, scientists gain a detailed view of how the brain is built and functions. Recent draft…
-
IFITM3-MET Interaction Drives Osimertinib Resistance in NSCLC
Overview: A cytokine-driven route to osimertinib resistance in EGFR-mutant NSCLC Osimertinib has transformed treatment for patients with EGFR-mutant non-small cell lung cancer (NSCLC) but resistance remains a critical hurdle. A combination of clinical data, tumor profiling, and functional studies now implicates IFITM3, a small antiviral membrane protein, in mediating resistance. The key finding is that…
-
Planarian stem cells reveal global signals drive regeneration
Planarian stem cells challenge the traditional view of stem cell niches In a breakthrough study published in Cell Reports, scientists from the Stowers Institute for Medical Research reveal that planarian stem cells do not rely on a fixed, nearby niche to regulate their fate. Instead, these cells respond to signals emanating from distant parts of…
-
Tiny Regenerative Worm Offers New Clues for Human Tissue Repair
Planarian Stem Cells May Rewrite Our Understanding of Regeneration In a breakthrough shift for regenerative biology, researchers at the Stowers Institute for Medical Research have shown that planarian stem cells can ignore their immediate neighbors and instead respond to signals farther away in the body. This discovery, published in Cell Reports, challenges the long-held view…
-
Planarian stem cells defy niche signals, unlocking the secrets of regeneration
Planarian stem cells reveal a new horizon in tissue regeneration Planarian flatworms have long fascinated scientists with their extraordinary regenerative powers. A new study from the Stowers Institute for Medical Research, published in Cell Reports, shows that planarian stem cells may not rely on a local niche in the way many other organisms do. Instead,…