Tag: Sepsis
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WHO sound alarm on global antibiotic resistance as reports show rising infections resistant to treatments
Global alarm over antibiotic resistance The World Health Organization (WHO) has issued a stark warning: antibiotic resistance is spreading worldwide, with one in six laboratory-confirmed bacterial infections in 2023 showing resistance to standard treatments. The Global Antimicrobial Resistance and Use Surveillance System (GLASS) data from more than 100 countries indicate that resistance grew in over…
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Sepsis documentary shines a light on a silent killer: stories of loss, love and survival
Sepsis touches every corner of life When a disease moves quietly through a family, it often leaves an invisible trail of questions. Sepsis is one of those conditions that can strike anyone, at any time, regardless of age or health. A new documentary, Sepsis: A Story of Loss, Love and Survival, brings eight family-led accounts…
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Sepsis: A Documentary Spotlight on Loss, Love, and Lifesaving Awareness
Sepsis: A Story That Hits Home A new documentary, Sepsis: A Story of Loss, Love and Survival, brings a human face to the serious condition that can affect anyone, at any time. Through personal narratives from families touched by sepsis, the film underscored a stark message: awareness and early recognition can change outcomes. The project…
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New Sepsis Documentary Highlights It Can Happen to Anyone: A Story of Loss, Love, and Survival
Sepsis: A Quiet Killer That Touches Anyone Sepsis can strike without warning, even when a person is living with a known chronic illness or a recent medical hurdle. A new documentary, Sepsis: A Story of Loss, Love and Survival, brings forward eight intimate stories to remind the public that sepsis can happen to anyone, anywhere,…
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Decoding Sepsis Signaling and Metabolic Dysregulation
Introduction: The Signaling Web Behind Sepsis Sepsis is a life-threatening syndrome driven by dysregulated immune responses and widespread metabolic disruption. Modern research reveals that sepsis emerges from an intricate network of signaling pathways that control inflammation and cellular energy. By decoding these networks—rather than focusing on a single target—we can better understand disease progression and…
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Decoding Signaling Networks and Metabolic Dysregulation in Sepsis: Toward Dynamic, Multi-Target Therapies
Introduction: Sepsis as a Signaling and Metabolic Challenge Sepsis is a complex, life-threatening syndrome driven by dysregulated immune responses, systemic inflammation, and widespread metabolic disruption. Traditional treatments, centered on antibiotics and early goal-directed therapy, often fall short due to the dynamic and heterogeneous nature of the disease. A growing body of research points to a…
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Decoding Signaling Networks and Metabolic Dysregulation in Sepsis
Understanding Sepsis: A Web of Signaling and Metabolism Sepsis is a life-threatening syndrome arising from infection that triggers a dysregulated immune response and widespread organ dysfunction. Modern research paints a picture of sepsis not as a single pathway anomaly but as a complex network of interlocking signaling cascades and metabolic changes. Central to this network…
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Prognostic Value of Low-Cost WBC Indices and Procalcitonin in Rwandan Sepsis ICUs
Introduction: Sepsis in resource-limited settings Sepsis remains a leading cause of mortality worldwide, with sub-Saharan Africa facing unique challenges due to limited ICU capacity and diagnostic resources. In Rwanda, where ICU beds are scarce and advanced laboratory testing is not universally accessible, practical biomarkers are essential for early risk stratification and targeted therapy. This prospective…
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Prognostic Value of Low-Cost WBC Indices and Procalcitonin for Mortality in Rwandan Sepsis Patients: A Prospective ICU Study
Overview: Sepsis, biomarkers, and context in Rwanda Sepsis remains a leading cause of death globally, with resource-limited settings bearing a disproportionate burden. In Rwanda, where ICU capacity is constrained, identifying simple, affordable prognostic tools is critical. This study examines whether low-cost white blood cell (WBC) indices and procalcitonin (PCT) levels can predict mortality among adults…
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Prognostic value of low-cost WBC indices and PCT for mortality in Rwandan sepsis patients: A prospective ICU study
Background Sepsis remains a leading cause of death worldwide, with higher burden and diagnostic challenges in low-resource settings. In sub-Saharan Africa, limited ICU capacity and lab infrastructure complicate timely risk stratification. This study evaluates whether low-cost white blood cell (WBC) indices and procalcitonin (PCT) can predict mortality among adults with suspected sepsis admitted to two…