Tag: retrospective study
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Streamlining Care with Patient Navigation: Improving Timely Anti-HER2 Therapy in Early Breast Cancer in LMICs
Background and Rationale In early breast cancer, HER2-positivity demands timely anti-HER2 therapy to optimize outcomes. In low- and middle-income countries (LMICs), health-system constraints—ranging from fragmented care pathways to access barriers—often delay treatment initiation. This retrospective cohort study investigates whether a structured Patient Navigation Program can shorten the time from diagnosis to the start of anti-HER2…
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Streamlining care through patient navigation: a retrospective cohort study of timely anti-HER2 therapy in early breast cancer in a LMIC
Introduction Early HER2-positive breast cancer requires timely initiation of anti-HER2 therapy to optimize outcomes. In low- and middle-income countries (LMICs), health-system constraints—ranging from diagnostic delays to treatment access barriers—can slow this process. This retrospective cohort study examines whether a structured Patient Navigation Program (PNP) can reduce the time from diagnosis to initiation of anti-HER2 therapy…
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Could COVID Vaccines Help Fight Cancer? What the New Findings Mean
Could the COVID-19 vaccine help in the fight against cancer? Emerging research is stirring new questions about how COVID-19 vaccines, particularly mRNA vaccines, might interact with cancer therapies. A study analyzing more than 1,000 patient records suggests that receiving a COVID-19 mRNA vaccine within 100 days of starting immunotherapy was associated with longer survival for…
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Could COVID Vax Fight Cancer? New Findings Surprise on Immunotherapy Outcomes
Can a COVID-19 Vaccine Help Treat Cancer? Recent research from the United States has sparked interest in whether COVID-19 vaccines, particularly mRNA vaccines, might influence cancer outcomes when given alongside immunotherapy. In a retrospective analysis of more than 1,000 patients with advanced lung cancer or metastatic melanoma, researchers found that those who received a COVID-19…
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User Engagement, Demographics, and Health Status of the My ME-BYO Record: A Retrospective Study
Overview The My ME-BYO Record app, developed and managed by the Kanagawa Prefectural Government in Japan, serves as a unique public-sector mHealth tool. Launched in 2017, it records health data, medication use, and physical activity, while the ME-BYO index—introduced in 2020—visualizes an individual’s predisease state to encourage behavioral change. This retrospective study analyzes real-world data…
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GNRI Predicts Adverse Outcomes in Elderly BSI Patients
Introduction Bloodstream infections (BSIs) pose a severe threat to elderly patients, who are disproportionately affected by malnutrition and frailty. The Geriatric Nutritional Risk Index (GNRI), a simple calculator using albumin, height, and weight, has emerged as a practical tool for predicting morbidity and mortality in hospitalized seniors. This retrospective study from a large Beijing tertiary…
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GNRI Predicts Adverse Outcomes in Elderly with Infections: A Retrospective Study
Why GNRI matters for the elderly with bloodstream infections Bloodstream infections (BSIs) place a heavy burden on hospitalized patients, and the impact is often worse in older adults. Malnutrition is a common comorbidity in the elderly and can worsen infection outcomes by impairing immune function and healing. The Geriatric Nutritional Risk Index (GNRI) is a…