Tag: regenerative medicine
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IMB: The Global Research Powerhouse Transforming Medicine
Introduction: A global research powerhouse taking shape Over the past 25 years, the University of Queensland’s Institute of Molecular Bioscience (IMB) has established itself as a global force in biomedical innovation. From breakthroughs in venom-derived therapies to the development of disease-modifying strategies, IMB has consistently translated basic science into tangible health benefits. Its work spans…
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Checkpoint inhibitors reveal tissue repair role, offering hope for chronic wounds
Unveiling a new function for a familiar immune brake Checkpoint inhibitors are well known for their role in cancer therapy, where they release the immune system’s brakes to attack tumor cells. In a surprising twist, researchers from the University of Zurich (UZH) have uncovered a second, equally important function: TIGIT, a checkpoint protein, promotes tissue…
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TIGIT: Immune Checkpoint Promoter of Tissue Healing Could Change Fibrosis and Wound Care
Groundbreaking finding: TIGIT helps tissue repair Researchers at the University of Zurich (UZH) have uncovered a surprising role for the immune checkpoint inhibitor TIGIT beyond its well-known function as a cancer therapy target. In a study led by Nicole Joller, the team demonstrated that TIGIT not only helps regulate immune responses during infections but also…
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Planarian stem cells reveal global signals drive regeneration
Planarian stem cells challenge the traditional view of stem cell niches In a breakthrough study published in Cell Reports, scientists from the Stowers Institute for Medical Research reveal that planarian stem cells do not rely on a fixed, nearby niche to regulate their fate. Instead, these cells respond to signals emanating from distant parts of…
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Tiny Regenerative Worm Offers New Clues for Human Tissue Repair
Planarian Stem Cells May Rewrite Our Understanding of Regeneration In a breakthrough shift for regenerative biology, researchers at the Stowers Institute for Medical Research have shown that planarian stem cells can ignore their immediate neighbors and instead respond to signals farther away in the body. This discovery, published in Cell Reports, challenges the long-held view…
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Planarian stem cells defy niche signals, unlocking the secrets of regeneration
Planarian stem cells reveal a new horizon in tissue regeneration Planarian flatworms have long fascinated scientists with their extraordinary regenerative powers. A new study from the Stowers Institute for Medical Research, published in Cell Reports, shows that planarian stem cells may not rely on a local niche in the way many other organisms do. Instead,…
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Lab-grown embryo models reveal how blood and heart cells form in early development
Introduction: A leap in modeling early human development University of Cambridge scientists have created three-dimensional, embryo‑like structures from human stem cells that self‑organize and mimic aspects of very early human development. Named hematoids, these models reproduce the formation of blood stem cells and beating heart cells in a lab setting, offering a window into the…
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Lab-grown embryo models Hematoids mimic early human blood and heart development
Groundbreaking lab-grown embryo models reveal early blood formation Researchers at the University of Cambridge have created three-dimensional, embryo-like structures from human stem cells that replicate crucial early steps of human development. Named hematoids, these self-organising models begin producing blood stem cells within about two weeks in the lab, offering a window into how the human…
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Lab-grown embryo models mimic natural formation of blood and heart cells
Overview: A window into early human development Scientists at the University of Cambridge have engineered three‑dimensional, embryo‑like structures from human stem cells that replicate key features of very early human development. These structures, named hematoids, self‑organize to form tissues and, notably, produce blood stem cells, offering a promising platform to study how the human body…
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Lab-grown Embryo Model Produces Blood Cells for Therapy
Breakthrough: Lab-grown embryo-like structures form blood progenitors Researchers have created embryo-like structures from human stem cells in the laboratory that spontaneously generate blood cells. This milestone could one day enable bone marrow–related therapies using a patient’s own cells, reducing the risk of immune rejection and expanding treatment options for blood disorders. How the model works…