Tag: Radiopharmaceuticals
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Fast SPECT Acquisitions Enable STP Dosimetry for 177Lu-PSMA in mCRPC
Overview Single time-point (STP) dosimetry is gaining traction in the management of metastatic castration-resistant prostate cancer (mCRPC) treated with Lutetium-177 labeled PSMA (177Lu-PSMA). This approach aims to estimate absorbed radiation doses with a single post-therapy imaging session, typically around 48 hours, reducing imaging burden and resource use compared with traditional multi-time-point (MTP) dosimetry. Here we…
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Lu-177 PNT2002 Combined with SBRT Delays Prostate Cancer Progression
Overview New data presented at the American Society for Radiation Oncology (ASTRO) meeting suggest that adding the radiopharmaceutical Lu-177 PNT2002 to stereotactic body radiation therapy (SBRT) can significantly delay disease progression in men with oligometastatic, or limited, prostate cancer. The LUNAR trial compared SBRT alone to a two-cycle course of Lu-177 PNT2002 followed by SBRT,…
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Radiopharmaceutical Therapy Boosts Radiation to Slow Prostate Cancer
New Findings from the LUNAR Trial A landmark phase II study, known as the LUNAR trial, reports that people with recurrent prostate cancer and a limited number of metastases lived significantly longer without disease progression when a radiopharmaceutical drug was given before targeted radiation therapy, compared with high-precision radiation alone. The randomized study evaluated whether…