Tag: Radiation Therapy
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SUPREMO Trial: Rethinking Postmastectomy Radiotherapy
Overview: A Shift in Postmastectomy Strategy The international phase 3 SUPREMO trial is reshaping how clinicians treat intermediate-risk early breast cancer (eBC) after mastectomy. The study, officially registered as ISRCTN61145589, investigated whether omitting chest-wall irradiation could maintain survival outcomes while reducing treatment-related toxicity. Historically, postmastectomy radiotherapy (PMRT) has been standard care for various levels of…
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Modern Therapies Challenge Radiation’s Role in Early Breast Cancer Survival
Rethinking Postmastectomy Radiation in Early Breast Cancer New evidence from the international phase 3 SUPREMO trial is prompting clinicians to rethink the standard use of chest-wall irradiation after mastectomy for patients with intermediate-risk early breast cancer (eBC). The study explored whether omitting radiotherapy could maintain survival while reducing treatment-related harms, a question that directly affects…
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Breast Cancer: Radiation May Be Unnecessary for Many Patients
New findings question the routine use of radiation in early breast cancer Radiation therapy has long been a cornerstone of breast cancer treatment, helping to reduce local recurrence after surgery. In recent years, however, many doctors have begun reevaluating its role for patients with early-stage disease. Advances in imaging, tumor biology, and systemic therapies have…
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Stereotactic body radiation therapy and the TORPEDO trial: A new approach for inoperable pancreatic cancer
Overview: SBRT as a potential option for inoperable PDAC Pancreatic ductal adenocarcinoma (PDAC) remains one of the most challenging cancers to treat, especially when surgical options are off the table. For patients with non-metastasized yet inoperable disease, there is a critical need for effective, well-tolerated therapies. The TORPEDO trial investigates stereotactic body radiation therapy (SBRT)…
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Study Identifies New Approach to Protect the Brain During Radiation Therapy
Overview: A New Strategy to Shield the Brain During Radiation Cancer survivors often face cognitive challenges after treatment. In brain cancer, cranial radiation therapy is a standard lifesaving intervention, but it can cause lasting problems with memory, attention, and executive function. A recent experimental study from the University of California, Irvine, led by Munjal Acharya,…
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New Brain-Sparing Approach in Radiation Therapy Could Protect Cancer Survivors’ Cognition
Groundbreaking step toward protecting the brain during radiation therapy Radiation therapy remains a cornerstone in treating brain cancers, but its cognitive side effects can shadow the relief of cancer remission. Up to 70% of survivors report challenges with memory, attention, and executive function, profoundly affecting daily life and independence. A new study from UC Irvine…
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New approach protects the brain from radiation-induced cognitive decline
New research offers a targeted safeguard for brain cancer patients undergoing radiation therapy For many cancer survivors, the battle isn’t over once tumors are treated. Cognitive challenges—trouble with memory, attention, and concentration—can persist after cranial radiation therapy. In brain cancer patients, up to 70% report some form of cognitive impairment, a burden that affects independence…
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Biden Begins Radiation Therapy for Prostate Cancer: What It Means for His Care
Overview: Biden Starts Radiation Therapy for Prostate Cancer Former President Joe Biden is undergoing radiation therapy as part of his treatment for prostate cancer, his spokesperson confirmed. At 82, Biden is also receiving hormone treatment as doctors manage an aggressive form of the disease that had spread to the bones. The radiation plan is described…


