Tag: psychiatric biomarkers
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Mosaic Loss and Young-Onset Psychiatric Disorders: Exploring mCAs in Blood and Brain Tissues
Introduction: A New Window into Early-Onset Psychiatric Illness Psychiatric conditions such as schizophrenia (SCZ) and bipolar disorder (BD) often emerge in adolescence or early adulthood, underscoring the need to understand their roots long before full clinical syndromes develop. Recent research has highlighted mosaic chromosomal alterations (mCAs) as a potential contributor to brain function and psychiatric…
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Multi-System Biomarkers for Suicide Risk in Major Depressive Disorder
Understanding the Need for Multi-System Biomarkers in MDD Major Depressive Disorder (MDD) remains a leading cause of disability worldwide, with suicide risk presenting one of its most urgent clinical challenges. Traditional risk assessments rely on psychosocial factors and clinical history, but they often fail to capture the biological underpinnings that can signal imminent danger. A…