Tag: preclinical study
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A New Drug Shields Mitochondria to Prevent Kidney Injury in Mice
Researchers unveil a mitochondria-focused approach to preventing kidney injury Acute kidney injury (AKI) remains a serious and sometimes fatal complication in hospitalized patients, especially those facing sepsis, major surgery, or intensive care treatments. A new preclinical study from researchers at the University of Utah Health suggests a novel drug can protect kidney cells by preserving…
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New Drug Shields Mitochondria and Prevents Kidney Injury in Mice
Scientists unveil a breakthrough drug that protects mitochondria and guards against acute kidney injury Acute kidney injury (AKI) is a serious and sometimes fatal condition triggered by a range of stressors, from sepsis to surgical shock. It can rapidly impair short-term kidney function and increase the long-term risk of chronic kidney disease. In a new…
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Nanovaccine Promises New Hope Against HPV-Related Cancers
Groundbreaking Nanovaccine Targets HPV-Driven Cancers A new nanovaccine approach developed by researchers at UT Southwestern Medical Center has demonstrated remarkable efficacy against cancers caused by human papillomavirus (HPV) in a late-stage animal model. The study, described by the team as a significant step toward treating HPV-related malignancies, reports tumor eradication in animals with advanced, metastatic…
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McGill researchers develop breakthrough hydrogel to heal damage vocal cords
Researchers unveil a breakthrough hydrogel for vocal cord repair A team at McGill University has developed a novel hydrogel designed to repair damaged vocal cords, offering renewed hope for people affected by voice loss or chronically damaged vocal tissue. The injectable gel uses natural tissue proteins processed into a powder and reconstituted into a gel,…
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Vitamin C in the Brain Slows Alzheimer’s, i3S Study Reveals
New i3S findings connect brain vitamin C to slowed Alzheimer’s progression A research team at the i3S Research Center in Portugal has reported a striking finding: restoring vitamin C concentration inside brain microglia—the immune cells that patrol the nervous system—reinstates normal cellular behavior in preclinical models of Alzheimer’s disease. By ensuring effective vitamin C transport…
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Vitamin C in Brain May Slow Alzheimer’s: i3S Study Findings
Vitamin C in the brain could slow Alzheimer’s progression, new i3S findings suggest A recent study from the i3S research center in Portugal reports that replenishing vitamin C levels within the brain may delay the progression of Alzheimer’s disease in preclinical models. By focusing on microglia—the brain’s resident immune cells—the researchers demonstrate that restoring intracellular…
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Vitamin C Replenishment in the Brain Delays Alzheimer’s, New Study Suggests
New findings from a Portuguese research team A team at i3S, the health research hub in Portugal, reports a striking link between brain vitamin C balance and Alzheimer’s disease in preclinical models. The study suggests that transporting and normalizing vitamin C concentration inside microglia—the brain’s immune cells—restores their normal functioning, potentially altering the disease course…
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New Compound Blocks Lung Cancer Growth: Early Promise
Groundbreaking preclinical results A team of researchers from several institutions has reported encouraging preclinical results for a novel compound, tentatively named X-101, that blocks the growth of lung cancer cells. In laboratory experiments, the compound significantly reduced cancer cell proliferation across multiple non-small cell lung cancer (NSCLC) lines and hindered tumor growth in mouse models.…