Tag: precision oncology
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Ireland’s Largest Cancer Research Programme Secures €28m for Phase 2 Expansion
Ireland’s Largest Cancer Research Programme Secures €28m for Phase 2 Expansion precision Oncology Ireland (POI), Ireland’s flagship cancer research initiative, has received €28 million in co-funding to launch Phase 2. The announcement, made by Minister for Further and Higher Education, Research, Innovation and Science James Lawless, marks a major milestone in the country’s commitment to…
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POI Phase 2: €28m to Accelerate Ireland’s Precision Oncology
Ireland’s Largest Cancer Research Programme Enters Phase 2 Ireland is accelerating its commitment to personalized cancer care as Precision Oncology Ireland (POI) enters its second phase. With a newly approved €28 million co-funding package, POI aims to scale its cross-sector model and deepen patient involvement, turning research breakthroughs into real-world diagnostics and treatments. What POI…
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Life-Saving Checks: Early Cancer Detection and Prevention
Life-Saving Checks: Early Cancer Detection in India Meera, a 42-year-old school teacher, went for her first routine mammogram while feeling perfectly healthy. The scan revealed a tiny lesion too small to feel by hand. A biopsy confirmed early-stage breast cancer. She underwent surgery and radiation and was cancer-free within months. Her doctor’s calm reassurance and…
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Life-Saving Checks for Early Cancer Detection and Prevention
The silent threat we can defeat: why early cancer detection matters Cancer often grows quietly, giving little or no warning signs until it is advanced. Meera’s story—where a routine mammogram uncovered a tiny lesion that biopsy confirmed as early breast cancer—illustrates a life saved by preventive screening. When cancers are detected early, treatment is simpler,…
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Life-saving checks for early detection of cancer and prevention
Why early detection matters Cancers often grow quietly, without obvious symptoms. When caught early, they are usually easier to treat, require less aggressive therapies, and offer substantially higher chances of cure. Public health programs that promote regular screening and risk-based prevention can turn cancer from a life-changing diagnosis into a manageable condition or even prevent…
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A Human-LLM Collaborative Annotation Approach for Screening Precision Oncology Randomized Controlled Trials
Introduction Systematic reviews in precision oncology rely on screening thousands of articles to identify randomized controlled trials that evaluate targeted therapies, biomarkers, and patient outcomes. This manual annotation process is labor-intensive, time-consuming, and susceptible to variability across reviewers. Large language models (LLMs) offer rapid classification and data extraction, but their reliability can be uneven without…
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A Human-LLM Collaborative Annotation Approach for Screening Precision Oncology RCT Articles
Introduction Systematic reviews in precision oncology rely on identifying randomized controlled trials (RCTs) to compare therapies and guide clinical decisions. However, screening thousands of articles to find eligible RCTs is labor-intensive and prone to human error. While supervised learning can accelerate this process, it often demands large labeled datasets and careful tuning, especially for nuanced…
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A human-LLM collaborative annotation approach for screening articles on precision oncology randomized controlled trials
Why a human-LLM collaborative approach matters Systematic reviews in precision oncology require screening thousands of articles to identify randomized controlled trials (RCTs) that illuminate biomarker-driven therapies and targeted interventions. Manual screening, while thorough, is time-consuming and resource-intensive. Large language models (LLMs) can accelerate triage by quickly categorizing relevance and extracting key trial details, but their…
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The Silent Revolution of Patient-Derived Organoids in Oncology
The Silent Revolution: Patient-D Derived Organoids in Oncology In modern oncology, a quiet revolution is unfolding. Patient-derived organoids, or PDOs, are three-dimensional cultures grown from a patient’s tumor tissue. They faithfully mirror the architecture, cellular diversity, and functional traits of the original tumor far better than traditional two-dimensional models. By recapitulating the tumor microenvironment, PDOs…
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IIT-Madras launches cancer genome and tissue bank to advance India’s precision oncology
Revolutionizing cancer care in India Cancer remains a leading global killer, and India faces a rising burden that calls for therapies tailored to its diverse population. IIT-Madras is answering that call with a pioneering cancer genome and tissue bank. The initiative aims to collect and study thousands of tumor samples, enabling researchers to test therapies…