Tag: Pongo pygmaeus
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Pitheci Mitochondrial Genome Illuminates Orangutan Malaria Lineage
New mitochondrial genome sequence of Plasmodium pitheci from Bornean orangutans The mitochondrial (mt) genome of Plasmodium pitheci, the malaria parasite morphologically identified in Bornean orangutans (Pongo pygmaeus), has now been sequenced and analyzed, providing a crucial genetic reference for this Asian NHP malaria lineage. This study fills a long-standing gap in molecular characterization, moving beyond…
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Mitochondrial Genome of Plasmodium pitheci: Insights from Bornean Orang‑utan Malaria
Introduction: Plasmodium pitheci and the orang‑utan malaria puzzle Malaria parasites in non-human primates (NHP) span over 250 Plasmodium species that infect humans and other primates alike. Among Asian NHPs, orang‑utans (Pongo spp.) host several malaria lineages, including Plasmodium pitheci. Although previous work has described morphological infections and certain genetic markers, a fully validated mitochondrial (mt)…