Tag: polygenic risk score


  • Genetic Resilience to COPD: A Distinct Subtype in Smokers with High Genetic Risk

    Genetic Resilience to COPD: A Distinct Subtype in Smokers with High Genetic Risk

    Understanding genetic resilience to COPD in smokers Chronic obstructive pulmonary disease (COPD) remains a major health challenge, yet not all smokers with a high genetic risk develop the condition. Recent research introduces a new concept: genetic resilience to COPD. By examining individuals who smoke and carry a high polygenic risk score (PRS) for COPD but…

  • Genetic Resilience: A Distinct COPD Subtype In Smokers With High Genetic Risk

    Genetic Resilience: A Distinct COPD Subtype In Smokers With High Genetic Risk

    Understanding Genetic Resilience in COPD COPD shows substantial variability in how it develops among people who smoke. While a genetic risk score helps predict who is more likely to develop COPD, many individuals with high genetic risk do not actually develop the disease. Recent research introduces the concept of genetic resilience to COPD—a clinically meaningful…

  • Genetic Resilience to COPD: A Distinct Subtype in Smokers

    Genetic Resilience to COPD: A Distinct Subtype in Smokers

    Understanding genetic resilience in COPD Cigarette smoking remains the leading environmental driver of chronic obstructive pulmonary disease (COPD), yet not all smokers develop the disease. Recent research introduces the concept of genetic resilience: individuals who carry a high genetic risk for COPD yet show no airflow obstruction. By studying this resilient group, scientists aim to…