Tag: Pnas study
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Researchers Unveil How a Membrane Protein Motif Stabilizes Protein Architecture
New Insights into Membrane Protein Architecture Scientists at Scripps Research have unlocked fresh understanding of how membrane proteins—crucial players in transport, signaling, and cellular adhesion—achieve and maintain their complex shapes within the cell’s lipid envelope. Published in the Proceedings of the National Academy of Sciences on October 7, 2025, the study presents a computer-guided approach…
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Disabling a Cellular ‘Entry Code’ Could Stop Deadly Rotavirus Infection
New Target in the War Against Rotavirus Rotavirus remains a leading cause of severe dehydrating diarrhea in infants and young children, claiming more than 128,500 lives globally each year despite broad vaccination efforts. In the United States, a worrying trend toward waning vaccine uptake has coincided with rising rotavirus cases in recent years. A team…
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Rotavirus Infection: New Host-Targeting Therapy Avenues
Overview: A new angle in the fight against rotavirus Rotavirus remains a leading cause of severe dehydrating diarrhea in infants and young children worldwide, responsible for thousands of deaths annually despite vaccines. Recent work from Washington University School of Medicine in St. Louis has spotlighted a host-based vulnerability that rotavirus exploits to infect cells. By…