Case at a Glance Juvenile hemochromatosis, or hereditary hemochromatosis type 2A, is a rare autosomal recessive disorder driven by mutations in the HJV gene. The condition causes severe systemic iron overload with multiorgan involvement, frequently affecting endocrine and skeletal health. This case describes a 32-year-old woman who presented with secondary amenorrhea, progressive skin hyperpigmentation, arthritis,…