Tag: pharmacology
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Drugs Without Nausea: Scientists Target Brain Circuits to Separate Side Effects from Weight-Loss Benefits
Overview: Aiming for Nausea-Free Weight-Loss Drugs Nausea has long been a common hurdle for people using weight-loss medications such as Ozempic and other GLP-1 receptor agonists. While these drugs can help curb appetite and promote weight loss, the unpleasant side effect of nausea can limit adherence and diminish quality of life. In response, scientists are…
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Overcoming Nausea: The Next Wave of Weight-Loss Drugs and Safer Experiences
Search for a ‘painless’ path to weight loss Millions of Americans have found success with prescription medications like Wegovy and Zepbound, which help reduce appetite and boost weight loss. Yet the journey isn’t the same for everyone. A common obstacle is nausea, a side effect that can range from mild discomfort to significant disruption in…
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Brain scientists pursue nausea-free weight-loss drugs amid GLP-1 breakthroughs
Overview: The quest for nausea-free weight-loss medications Millions of Americans have achieved impressive weight loss with medications such as Wegovy and Zepbound, which target the body’s GLP-1 pathways to curb appetite and boost metabolic effects. Yet the journey with these drugs isn’t without rough edges. Nausea, vomiting, and other gastrointestinal side effects remain common early…
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Brain scientists pursue nausea-free weight-loss drugs to improve outcomes
Overview: The quest for nausea-free weight-loss drugs Across the United States and beyond, millions have found success shedding pounds with medications such as Wegovy and Zepbound. These GLP-1 receptor agonists help reduce appetite and slow digestion, leading to meaningful weight loss for many individuals. Yet the journey isn’t without its rough edges. A sizable share…
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Sea Sponge Molecule Shows Promise in Anti-Cancer Research
Introduction: A natural source, a scientific leap Scientists have long turned to the ocean for medicinal clues, and a recent development adds a significant entry to that archive. Chemists have synthesized a complex molecule found in sea sponges off the coast of South Korea, a compound that researchers believe could play a role in fighting…
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Sea Sponge Molecule Shows Promise in Cancer Fight
Groundbreaking Synthesis of a Sea Sponge Molecule A team of chemists has achieved a breakthrough by synthesizing a complex molecule originally found in sea sponges off the coast of South Korea. The molecule, a rare natural product, drew scientific attention for its potential anti-cancer properties. The work, published in the prestigious journal Science, lays the…
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Reducing Sleep Drugs Improves Life Quality for Older Adults
Overview: Sleep Drug Use and Aging As people age, sleep problems are common, and many older adults turn to medications to help them rest. A recent study published online on October 24 in The Lancet Regional Health — Americas suggests that reducing future use of sleep medications could lead to healthier lives for seniors, with…
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New Malaria Drug Could Be a Life-Saver as Standard Therapy Shows Signs of Weakness
Rising concerns about current malaria treatments For decades, artemisinin-based combination therapies (ACTs) have been the backbone of malaria treatment, delivering rapid symptom control and reducing transmission when used correctly. Yet scientists have warned that the long, heavy demand on these drugs—paired with evolving resistance—could undermine a global progress milestone. In regions where resistance has crept…
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Opioid Receptors in Motion Reveal Paths to Safer Painkillers
Unlocking the Dynamics of Mu-Opioid Receptors For decades, scientists have understood that opioids alleviate pain by binding to mu-opioid receptors in the brain and nervous system. Yet the precise chain of events that follows this binding remained cloudy. Recent research, focusing on the real-time behavior of these molecular switches, is shedding light on why some…
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Opioid receptors in motion: new clues for safer painkillers
Understanding the moving target: mu-opioid receptors For decades, scientists have known that opioids relieve pain by binding to mu-opioid receptors in the brain. These molecular switches, when activated, set off a cascade of signals that dull the perception of pain. But the exact sequence of events inside the receptor remained murky. A recent wave of…