Tag: patient-derived organoids
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The Silent Revolution of Patient-Derived Organoids in Oncology
The Silent Revolution: Patient-D Derived Organoids in Oncology In modern oncology, a quiet revolution is unfolding. Patient-derived organoids, or PDOs, are three-dimensional cultures grown from a patient’s tumor tissue. They faithfully mirror the architecture, cellular diversity, and functional traits of the original tumor far better than traditional two-dimensional models. By recapitulating the tumor microenvironment, PDOs…
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Silent Revolution of Patient-Derived Organoids in Oncology
Introduction: A Silent Revolution in Cancer Research The emergence of patient-derived organoids (PDOs) has quietly transformed oncology, enabling models that closely mirror human tumors. These three-dimensional structures, established from patient tissues—spanning gastrointestinal, pulmonary, breast, and other cancers—recreate key features of the tumor microenvironment (TME) and preserve intratumoral heterogeneity. As powerful platforms for drug screening, neoantigen…