Tag: PAR2
-
Innovative Approaches Target PAR2 Receptor to Alleviate Gut Pain
New Avenues in the Fight Against Gut Pain Abdominal pain is a defining feature of many digestive disorders, including inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). As researchers search for treatments that specifically address gut pain, two complementary lines of evidence are emerging. First, a newly identified bacterial enzyme may regulate pain signaling…
-
Targeting PAR2: Innovative Pathways to Relieve Gut Pain
New Insights into a gut pain signaling axis Abdominal pain is a common thread across many digestive disorders, from inflammatory bowel disease (IBD) to irritable bowel syndrome (IBS). Recent research has zeroed in on PAR2, a receptor located on the gut lining and pain-sensing nerves, as a pivotal driver of gut pain. PAR2 becomes activated…
-
Targeting PAR2: A Two-Pronged Strategy Uses Bacterial Enzymes and Nanoparticles to Fight Gut Pain
New Avenues in Gut Pain Management Abdominal pain is a defining symptom of many digestive disorders, from inflammatory bowel disease (IBD) to irritable bowel syndrome (IBS). A pair of pioneering studies is pushing the boundaries of how researchers might treat gut pain by focusing on PAR2, a receptor that drives pain signaling in the gut.…