Tag: ovarian toxicity
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Lauric Acid and Levodopa Mitigate Manganese-Induced Ovarian Toxicity in Mice Through Antioxidative, Anti-Inflammatory, and Steroidogenic Pathways
Overview Manganese, a naturally occurring element, can exert toxic effects on the female reproductive system at high exposure levels. Recent experimental work in BALB/c mice explored whether two compounds, lauric acid and levodopa, individually or together, can attenuate manganese-induced ovarian toxicity. The study centers on antioxidative, anti-inflammatory, and steroidogenic pathways as key mediators of protection.…
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Lauric acid and levodopa curb manganese ovarian toxicity
Overview Manganese is an essential trace element with a complex role in health and disease. While necessary in small amounts for enzyme function, excess manganese exposure can disrupt ovarian function and reproductive health. Recent preclinical work using BALB/c mice demonstrates that combinations of lauric acid and levodopa may attenuate manganese-induced ovarian toxicity. The protective effects…