Tag: osteosarcoma
-
Genetic Link to Osteosarcoma Found: SMARCAL1 Gene Inheritance Raises Risk in Children
Breakthrough in Pediatric Cancer Genetics A collaborative study led by researchers at Cleveland Clinic Children’s has identified an inherited genetic factor that may elevate the risk of osteosarcoma, the most common malignant bone tumor in children and young adults. Published in the Journal of Clinical Oncology, the work analyzed genetic data from thousands of cancer…
-
Genetic Link Identified: SMARCAL1 Mutations Raise Osteosarcoma Risk in Children
Groundbreaking discovery links SMARCAL1 to pediatric osteosarcoma A team from Cleveland Clinic Children’s has identified a previously unknown genetic factor that may increase the risk of developing osteosarcoma, the most common malignant bone tumor in children and young adults. Published recently in the Journal of Clinical Oncology, the study analyzed genetic data from thousands of…
-
Cleveland Clinic Team Uncovers Genetic Link to Osteosarcoma
Groundbreaking discovery ties SMARCAL1 gene to pediatric osteosarcoma A team at Cleveland Clinic Children’s has identified a genetic factor that may increase the risk of developing osteosarcoma, the most common malignant bone tumor in children and young adults. The study, recently published in the Journal of Clinical Oncology, analyzed genetic data from nearly 6,000 children…
-
Genomic study reveals epigenetic drivers in osteosarcoma guiding tailored therapies
New genomic insights illuminate osteosarcoma biology Osteosarcoma, the most common bone cancer in children and adolescents, has long challenged clinicians with its aggressive course and tendency toward chemotherapy resistance. A new study led by Livia Garzia, PhD, Nada Jabado, MD, PhD, and Claudia Kleinman, PhD, from The Research Institute of the McGill University Health Centre…
-
Genomic Insights Offer Hope for Tailored Osteosarcoma Therapies
New genomic study highlights epigenetic drivers of osteosarcoma An international team led by Livia Garzia, PhD, Nada Jabado, MD, PhD, and Claudia Kleinman, PhD, has unveiled important epigenetic features in osteosarcoma, offering fresh directions for prognosis and treatment. The findings, published in Nature Communications, illuminate how epigenetic regulation shapes this aggressive bone cancer that primarily…