Tag: Nuclear Medicine
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Fast SPECT Acquisitions Enable STP Dosimetry for 177Lu-PSMA in mCRPC
Overview Single time-point (STP) dosimetry is gaining traction in the management of metastatic castration-resistant prostate cancer (mCRPC) treated with Lutetium-177 labeled PSMA (177Lu-PSMA). This approach aims to estimate absorbed radiation doses with a single post-therapy imaging session, typically around 48 hours, reducing imaging burden and resource use compared with traditional multi-time-point (MTP) dosimetry. Here we…
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Fast SPECT acquisitions enable single-time-point dosimetry for 177Lu-PSMA in metastatic prostate cancer
Introduction Targeted radionuclide therapy with Lutetium-177 labelled PSMA (177Lu-PSMA) has emerged as a leading option for metastatic castration-resistant prostate cancer (mCRPC). Traditional dosimetry often relies on multiple time-point imaging to capture radiopharmaceutical pharmacokinetics, which can create a substantial imaging burden, workload, and costs. Single time-point (STP) dosimetry, particularly at about 48 hours post-administration, offers a…
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GLP-1 Drugs May Skew PET-CT Scans: A Hidden Risk for Cancer Detection
Understanding the emerging imaging challenge with GLP-1 medications GLP-1 receptor agonists, including popular drugs like Ozempic, Wegovy, and Mounjaro, have transformed weight loss and diabetes management. Yet as usage surged—reported to have risen about 700% in the United States from 2019 to 2023—so have reports of unusual side effects. A less obvious consequence is their…
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Ga-68 DOTANOC PET/CT: A New Lens for Assessing Therapy Response in Cardiac Sarcoidosis
Introduction Cardiac sarcoidosis is an inflammatory granulomatous disease of the heart that carries substantial morbidity and mortality if not properly managed. Immunosuppressive therapy, often steroids, remains the cornerstone of treatment. While traditional imaging modalities help diagnose cardiac involvement, tracking the response to therapy requires reliable, repeatable biomarkers of inflammation. Recent prospective data from a study…
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Ga-68 DOTANOC PET/CT for Response Assessment in Cardiac Sarcoidosis: A Prospective Study
Introduction Cardiac sarcoidosis is an inflammatory granulomatous disease of the heart that carries significant morbidity and mortality. Immunosuppressive therapy is the cornerstone of treatment, aiming to reduce myocardial inflammation and preserve cardiac function. This prospective observational study evaluates the usefulness of Ga-68 DOTANOC PET/CT, a somatostatin receptor imaging modality, for assessing treatment response in cardiac…
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Revolutionizing Medical Imaging: The New Crystal Camera
Introduction to the New Crystal Camera The landscape of medical imaging is undergoing a transformative shift with the introduction of a groundbreaking crystal camera designed for nuclear medicine. This innovative technology, pioneered by scientists from Northwestern University and Soochow University in China, utilizes a perovskite-based detector to capture individual gamma rays with unprecedented precision. This…
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Revolutionizing Nuclear Medicine: The New Crystal Camera
Introduction to the Crystal Camera Revolution In a groundbreaking advancement, scientists from Northwestern University and Soochow University have developed a novel perovskite-based detector, transforming the world of nuclear medicine imaging. This new technology captures individual gamma rays with unprecedented precision, promising to enhance SPECT (single-photon emission computed tomography) imaging significantly. With potential applications in medical…