Tag: neuroimmunology
-
Autobahn Therapeutics Unveils Preclinical Data Supporting Restorative Neuroplasticity Mechanism of Elunetirom
New Preclinical Findings Spotlight a Restorative Neuroplasticity Mechanism Autobahn Therapeutics has presented new preclinical data for its investigational drug, Elunetirom, at the American College of Neuropsychopharmacology (ACNP) Annual Meeting. The research centers on a novel restorative neuroplasticity mechanism believed to promote recovery and resilience in neuropsychiatric and neuroimmunologic disorders. The findings add to the company’s…
-
Autobahn Therapeutics Unveils Preclinical Data on Elunetirom’s Restorative Neuroplasticity at ACNP Annual Meeting
Autobahn Therapeutics Highlights New Preclinical Data on Elunetirom Autobahn Therapeutics, a pioneering biotechnology company focused on restorative treatments for neuropsychiatric and neuroimmunologic disorders, announced new preclinical findings for elunetir… at the American College of Neuropsychopharmacology (ACNP) annual meeting. The presentation contributes to growing evidence that elunetirom could drive restorative neuroplasticity, a therapeutic paradigm aimed at…
-
Cryo-EM Maps Autoantibody Hotspots on NMDA Receptors in Autoimmune Encephalitis
New Cryo-EM insights reveal antibody hotspots on NMDA receptors Researchers have leveraged cutting-edge Cryo-Electron Microscopy (Cryo-EM) to pinpoint where autoantibodies most often target NMDA receptors in anti-NMDAR encephalitis. This autoimmune condition, often described in public health circles as “Brain on Fire,” arises when the body’s immune system mistakenly attacks NMDA receptors in the brain, disrupting…
-
Cryo-EM Maps Spotlight Autoantibody Hotspots on NMDA Receptors for Anti-NMDAR Encephalitis Therapies
New Insights into Anti-NMDAR Encephalitis Autoimmune encephalitis linked to anti-NMDA receptor (NMDAR) antibodies has earned the nickname “Brain on Fire” for its dramatic neuropsychiatric symptoms and rapid progression. A groundbreaking study published in Science Advances leverages cryo-electron microscopy (cryo-EM) to map where autoantibodies most often bind on the NMDAR complex. The findings offer a clearer…
-
Soft Wireless Bioelectronic Implant Targets the Splenic Nerve to Reduce Inflammation
New Frontiers in Treating Chronic Inflammation For millions living with chronic inflammatory diseases such as inflammatory bowel disease (IBD), managing flare-ups means navigating a complex landscape of medications, monitoring side effects, and weighing quality of life. A new study published in National Science Review unveils a promising avenue: a soft, wireless bioelectronic implant that targets…
-
Newly Identified Microglia Subtype Offers Protection Against Alzheimer’s Disease
Groundbreaking discovery: a protective microglia subtype In the ongoing effort to understand Alzheimer’s disease, researchers are turning the spotlight onto the brain’s immune sentinels: microglia. A newly identified subtype of these cells appears to play a protective role in the brain, potentially slowing the progression of Alzheimer’s disease. The finding, emerging from collaborations led by…
-
A New Microglia Subtype May Shield the Brain from Alzheimer’s
Breaking Discovery: A Protective Microglia Subtype Emerges In the ongoing quest to understand Alzheimer’s disease, scientists have long watched the brain’s resident immune cells, microglia, as both guardians and potential aggressors. A recent study by researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with other institutions, has identified a distinct microglia…
-
Investigating cannabidiol’s role in combating Alzheimer’s-related neuroinflammation
Background: the inflammation link in Alzheimer’s disease Alzheimer’s disease is commonly discussed in terms of plaques and tangles, but neuroinflammation is increasingly recognized as a driving force in its progression. Chronic immune activation within the brain can damage neurons and contribute to cognitive decline. Cannabidiol (CBD), a non-psychoactive component of cannabis, has demonstrated anti-inflammatory properties…