Tag: neuro-oncology
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Focused Ultrasound Shows Promise in Pediatric Brain Cancer Treatment
Breakthrough in Pediatric Brain Cancer Treatment Columbia University researchers have achieved a landmark step in the fight against pediatric brain cancer. In what researchers describe as the first demonstration that focused ultrasound can be safely used in children to aid drug delivery into the brain, the non-invasive technique shows promise as a way to improve…
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Focused Ultrasound Passes First Test in Treatment of Brain Cancer in Children
What is focused ultrasound and why it matters Focused ultrasound is a non-invasive technique that uses precisely targeted sound waves to temporarily and safely disrupt the barriers protecting the brain. By transiently opening the blood-brain barrier, it can enhance the delivery of chemotherapy and other therapeutics directly to brain tissue. This approach holds particular promise…
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Glioblastoma Erodes Skull Bone and Rewrites Immune Marrow
A deadly brain cancer with systemic consequences Glioblastoma, the deadliest form of brain cancer, is not contained to the brain alone. New research from Montefiore Einstein Comprehensive Cancer Center (MECCC) and the Albert Einstein College of Medicine shows the aggressive tumor also erodes the skull bone and reshapes the skull’s immune landscape. The findings, published…
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Avelumab with Radiation for Leptomeningeal Disease: Momentum
Introduction Leptomeningeal disease, in which cancer cells invade the membranes surrounding the brain and spinal cord, remains one of oncology’s most daunting challenges. Patients face rapid neurological decline, and survival is often measured in weeks to months. In a phase 1B study from Moffitt Cancer Center, researchers explored whether combining the immunotherapy drug avelumab with…
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Avelumab with Radiation: Hope for Leptomeningeal Disease
Leptomeningeal disease: a high-stakes challenge in oncology Leptomeningeal disease, where cancer cells spread to the membranes surrounding the brain and spinal cord, remains one of oncology’s most formidable complications. Patients diagnosed with this condition often face survival measured in weeks to months, and treatment options are historically limited. In a hopeful development, researchers at Moffitt…