Tag: maternal inheritance
-
Why Some Embryos Stall in Development: Centromere Clues from a New Study
Centromeres: The gatekeepers of early cell division Early embryo development hinges on a flawless handoff of parental DNA, a process that begins even before the first cell division. At the heart of this handoff are centromeres, special chromosome regions that act like handles during chromosome segregation. A key feature that marks these regions across generations…
-
Centromere Symmetry in Embryos: Why Some Embryos Stall
Centromeres and early embryo development When a sperm fertilizes an egg, the resulting zygote must quickly reassemble a unified genome from two parental sets of chromosomes. A key part of this process is the centromere, a chromosome region that acts like a handle for pulling the DNA apart during cell division. For decades, scientists believed…