Tag: Malaria
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Cost-Effective Travel Health: What Pre-Travel Interventions Deliver Real Value for Travelers
Why Pre-Travel Health Interventions Matter Travellers increasingly seek ways to stay healthy on international trips. A recent scoping review of 44 economic evaluations (spanning 1946–2023) highlights that certain pre-travel interventions can be cost-effective and reduce the burden of infectious diseases during and after travel. These findings matter for travelers planning trips as well as policymakers…
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New protein insights pave way for malaria transmission-blocking vaccines
New protein insights offer a path to blocking malaria transmission Malaria remains a global health challenge, infecting hundreds of millions and causing hundreds of thousands of deaths each year. While existing vaccines reduce the risk of infection, they do not fully prevent the parasite from spreading from person to person via mosquitoes. A multinational team…
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New insights into malaria proteins offer pathway to blocking parasite transmission
Unlocking the blueprint for blocking malaria transmission Researchers have made a pivotal advance in the fight against malaria by revealing the detailed structures of two of the parasite’s surface proteins. Using millions of high-resolution images gathered with cryo-electron microscopy, scientists from Radboud university medical center in the Netherlands and The Hospital for Sick Children Research…
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Mitochondrial Genome of Plasmodium pitheci in Bornean Orang-utans Reveals Close Relations Within Orang-utan Malaria Lineages
Background: Orang-utan malaria and the Plasmodium pitheci discovery Malaria in non-human primates (NHP) spans a diverse genus, with Plasmodium species infecting a broad host range. Among Asian NHPs, orang-utans (Pongo spp.) harbor Plasmodium pitheci and Plasmodium sylvaticum, parasites historically identified by morphology but lacking validated molecular characterization until now. The present work focuses on the…
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Pitheci Mitochondrial Genome Illuminates Orangutan Malaria Lineage
New mitochondrial genome sequence of Plasmodium pitheci from Bornean orangutans The mitochondrial (mt) genome of Plasmodium pitheci, the malaria parasite morphologically identified in Bornean orangutans (Pongo pygmaeus), has now been sequenced and analyzed, providing a crucial genetic reference for this Asian NHP malaria lineage. This study fills a long-standing gap in molecular characterization, moving beyond…
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Can an Ivermectin Pill Stop Malaria Transmission? What the Trials Show
What makes ivermectin a candidate for malaria control Malaria control hinges on reducing both the human parasite reservoir and the mosquito population that spreads it. Ivermectin, a long‑used antiparasitic, works inside the human body and can render mosquitoes dead or less able to transmit malaria after they feed on treated individuals. This unique mechanism distinguishes…
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Can Ivermectin Stop Malaria Transmission? What Trials Show
Can an ivermectin pill curb malaria transmission? The idea of using an ivermectin pill to curb malaria transmission is drawing renewed attention. Ivermectin, long used to treat parasitic worms and mass-administered for other diseases, can make the blood of treated people lethal to mosquitoes that bite them. The question researchers are asking is whether large‑scale…
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Can Ivermectin Stop Malaria Transmission? Trial Insights
Can ivermectin curb malaria transmission? Malaria remains a formidable public health challenge, with hundreds of thousands of lives lost annually and a persistent burden in parts of Africa. In parallel, researchers have explored a novel approach: using ivermectin, a long‑standing antiparasitic drug, to reduce malaria transmission by killing or weakening mosquitoes after they bite treated…


