Tag: macrophages
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Tuberculosis hijacks immune defenses to boost infection
How tuberculosis exploits immune defenses Scientists have uncovered a mechanism by which tuberculosis (TB) bacteria manipulate the very immune systems designed to stop them. The discovery sheds light on why humans and many animals remain highly vulnerable to TB, sometimes even when immune defenses are active. The bacteria appear to exploit a particular arm of…
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Study Unveils How Tuberculosis Exploits Immune Defenses to Promote Infection
New clues into TB’s clever hijacking of the immune system Scientists have uncovered mechanisms by which the bacterium that causes tuberculosis (TB) can turn the body’s own immune defenses to its advantage. The findings shed light on why humans and animals remain highly susceptible to TB and point toward new strategies for treatment and prevention.…
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Targeted Steroid Use Shows Promise Against TB
Targeted Steroid Use in TB: A Potential Complement to Antimicrobial Therapy Tuberculosis (TB) remains a global health challenge, affecting more than 10 million people each year. A recent study published in Scientific Reports explores a promising strategy: targeted use of steroids as an adjunct to standard antimicrobial therapy. The goal is not to replace antibiotics…
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Targeted Steroid Use Shows Promise Against Tuberculosis
New findings open doors for adjunctive steroid therapy in TB care Tuberculosis (TB) remains a global health challenge, affecting more than 10 million people each year. A new study published in Scientific Reports suggests that carefully targeted use of steroids could serve as a universal complementary treatment to bolster the body’s defense against TB while…
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Targeted Steroid Use Shows Promise Against Tuberculosis (TB)
Targeted Steroid Use in Tuberculosis: A New Complement to Antimicrobial Therapy Tuberculosis (TB) remains a global health challenge, affecting more than 10 million people each year. A new study published in Scientific Reports explores how a targeted steroid approach could enhance immune defense while curbing damaging inflammation. The findings point to a nuanced role for…
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Targeted Steroid Use Could Complement TB Treatment by Boosting Macrophage Defense
Overview: Rethinking Steroids in TB care Tuberculosis (TB) remains a global health challenge, infecting more than 10 million people annually and claiming around 1.25 million lives each year. While corticosteroids like dexamethasone are used in select TB scenarios, notably TB meningitis, their broader impact on immune cells—especially lung macrophages—has been unclear. A new study from…
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Targeted steroid use may boost macrophage defenses to fight TB
New insights into how dexamethasone could aid TB treatment Tuberculosis (TB) remains a global health challenge, affecting more than 10 million people annually and causing around 1.25 million deaths each year. Amid ongoing efforts to curb TB, researchers at Trinity College Dublin, based at St James’s Hospital in Dublin, are revisiting the role of steroids…
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Targeted steroid use may offer a universal complementary treatment to fight TB
Overview: A new angle on TB treatment Tuberculosis (TB) continues to be a major global health challenge, affecting more than 10 million people annually with about 1.25 million deaths each year. While steroids such as dexamethasone are already used in selected TB cases, the precise impact of these drugs on immune cells has remained unclear.…
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Lysosomal Acidity and Macrophage Function: A Balancing Act
The Role of Macrophages in Immune Defense Macrophages serve as the frontline defenders of our innate immune system, performing the crucial task of identifying and destroying invading pathogens. This process, known as phagocytosis, enables macrophages to engulf and neutralize harmful microbes. However, a delicate balancing act is required: while macrophages must effectively eliminate threats, they…
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Lysosomal Acidity in Macrophages: A Key Regulator of Immune Response
Understanding Macrophages and Their Role in Immunity Macrophages are the frontline defenders of our immune system. These cells play a crucial role in identifying and destroying pathogens. However, this essential function comes with the challenge of protecting surrounding tissues from potential damage during the process of phagocytosis, where they engulf and neutralize microbes. To achieve…