Tag: lung microbiome
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Aztreonam Recalibrates Pseudomonas aeruginosa and Streptococcus salivarius Interactions in COPD Patients
Overview: Intermicrobial Dynamics in COPD-Associated Infections Microbial communities shape the flow of energy and matter in chronic infections. In conditions like chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF), polymicrobial communities often drive virulence and antibiotic resistance. This study focuses on the interaction between two airway-associated microbes, Pseudomonas aeruginosa and Streptococcus salivarius, isolated from…
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Aztreonam Reconfigures Pseudomonas aeruginosa–Streptococcus salivarius Interactions in COPD-Associated Polymicrobial Infections
Overview: Microbial Interactions in Polymicrobial Lung Infections In chronic lung diseases such as COPD, cystic fibrosis, and COPD-related bronchial infections, microbial communities often comprise multiple species whose interactions determine disease trajectory and treatment outcomes. Polymicrobial infections can amplify virulence and antibiotic resistance, complicating management. This evolving field recognizes that even low-abundance microbes can steer the…
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Aztreonam Intervention Recalibrates Pseudomonas aeruginosa and Streptococcus salivarius Interactions in COPD-Associated Co-infections
Introduction: Polymicrobial infections in chronic lung disease Microbial communities shape energy flow and disease outcomes across ecosystems, including human chronic infections. In the lungs of COPD and cystic fibrosis patients, Pseudomonas aeruginosa often coexists with oral streptococci such as Streptococcus salivarius. These interactions influence virulence, antibiotic response, and disease progression. This study investigates how the…