Tag: LNP
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A New mRNA Therapy for Male Infertility: Promising Results in Mice
Introduction: A potential breakthrough in male infertility Researchers from The University of Osaka and Baylor College of Medicine have reported a novel mRNA-based approach to treating male infertility caused by genetic defects. By delivering synthetic messenger RNA (mRNA) via lipid nanoparticles (LNPs) directly into the testes, the team achieved restoration of spermatogenesis and produced viable…
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mRNA Therapy for Male Infertility: Breakthrough in Mouse Study
New mRNA Approach Targets Genetic Causes of Male Infertility Researchers from The University of Osaka and Baylor College of Medicine have unveiled a novel approach to treating male infertility caused by genetic defects. By delivering synthetic mRNA via lipid nanoparticles (LNPs) directly to the testes, scientists were able to restart sperm production in a mouse…
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Advancing Gene Editing: How Lipid Nanoparticles Are Shaping CRISPR Delivery
Introduction: The delivery bottleneck in CRISPR therapies CRISPR-based medicines hold the promise of treating a wide range of diseases, but their success hinges on effective delivery. Early efforts relied on viral vectors, especially adeno-associated viruses (AAVs), to ferry genetic material. While AAVs can deliver DNA, their payload size is limited and пациентов often develop immune…