Tag: levodopa
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Lauric Acid and Levodopa Mitigate Manganese-Induced Ovarian Toxicity in Mice via Antioxidative, Anti-Inflammatory, and Steroidogenic Pathways
Manganese is an essential trace element, yet excessive exposure can disrupt ovarian function. In BALB/c mice, high manganese levels have been linked to oxidative stress, inflammatory responses, and impaired steroidogenesis, collectively contributing to reduced fertility and endocrine disruption. Recent research explores how dietary interventions and pharmacologic agents might counteract these adverse effects. Among potential protectants,…
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Lauric Acid and Levodopa Mitigate Manganese-Induced Ovarian Toxicity in Mice Through Antioxidative, Anti-Inflammatory, and Steroidogenic Pathways
Overview Manganese, a naturally occurring element, can exert toxic effects on the female reproductive system at high exposure levels. Recent experimental work in BALB/c mice explored whether two compounds, lauric acid and levodopa, individually or together, can attenuate manganese-induced ovarian toxicity. The study centers on antioxidative, anti-inflammatory, and steroidogenic pathways as key mediators of protection.…
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Lauric acid and levodopa curb manganese ovarian toxicity
Overview Manganese is an essential trace element with a complex role in health and disease. While necessary in small amounts for enzyme function, excess manganese exposure can disrupt ovarian function and reproductive health. Recent preclinical work using BALB/c mice demonstrates that combinations of lauric acid and levodopa may attenuate manganese-induced ovarian toxicity. The protective effects…