Tag: Infertility
-
Dominique Nugent’s Best Christmas Gift: A Baby On The Way
A long journey to parenthood Dominique Nugent and her husband Paddy have spent years navigating the rollercoaster of fertility, facing more than one disappointment on the road to building a family. Like many couples, their path was filled with hope, worry, and urgent prayers for a positive sign that their dream could become a reality.…
-
Melatonin Supplementation and ART Outcomes: A Systematic Review and Meta-Analysis
Introduction Melatonin (MT) is more than a sleep hormone. It plays a multifaceted role in reproductive biology, influencing oocyte quality, embryo development, and endometrial receptivity. With infertility affecting millions worldwide, researchers have explored MT supplementation as a potential adjunct to assisted reproductive technology (ART) protocols. This article synthesizes current evidence from randomized trials and observational…
-
Stay With Me by Ayobami Adebayo: Love as a Test of Hope
Introduction: A Novel That Tests the Heart Ayobami Adebayo’s Stay With Me compellingly argues that love is not merely a feeling but a test—an ongoing trial shaped by culture, expectation, and the stubborn flame of hope. Set in Nigeria, the novel follows a couple navigating infertility, secrecy, and the burdens of a society with rigid…
-
Sperm Metabolic Switch Could Pave Way for New Fertility Therapies
Unlocking the energy behind fertilisation Researchers at Michigan State University have identified the molecular mechanism that powers sperm with a final burst of energy just before fertilisation. This discovery sheds light on how sperm switch from a low-energy state in the male reproductive tract to a high-energy, propulsion-ready state once they reach the egg, a…
-
Sperm Energy Switch Could Power New Fertility Therapies and Nonhormonal Contraceptives
Unlocking the Energy Switch Behind Sperm Activation Researchers from Michigan State University have identified a molecular mechanism that gives sperm a final energy boost just before fertilisation. This discovery could pave the way for innovative infertility therapies and safe, nonhormonal male contraceptives, addressing a long-standing gap in reproductive health options. To understand why this matters,…
-
Revealing the TMEM217-SLC9C1-sAC Axis: A Key Switch in Sperm Motility and Male Fertility
Understanding the Challenge: Male Infertility and Sperm Motility Infertility affects about one in six couples, and nearly half of these cases involve male factors. A common culprit is sperm that fail to swim effectively, a problem tied to the delicate signaling that powers tail movement. In a groundbreaking study from the University of Osaka, scientists…
-
TMEM217-SLC9C1-sAC Axis: New Sperm Motility Target
New findings illuminate a pivotal switch in sperm motility Infertility affects about one in six couples, and male factors account for roughly half of these cases. A new study from the University of Osaka has identified a crucial protein complex that acts as a switch controlling sperm movement, offering promising possibilities for diagnosis and treatment.…
-
New Insights Into Sperm Metabolism Could Transform Infertility Treatments
Groundbreaking Discovery Links Sperm Metabolism to Fertilization Researchers at Michigan State University have pinpointed a molecular “switch” that ramps up sperm energy production just before the final sprint to fertilize an egg. The finding, published in the Proceedings of the National Academy of Sciences, holds promise for reshaping infertility treatments and could pave the way…
-
Unlocking the Sperm Metabolic Switch: A Breakthrough for Infertility Treatments and Nonhormonal Contraception
New Insights into Sperm Metabolism Signal a Path Forward for Infertility Treatments Researchers at Michigan State University, in collaboration with Memorial Sloan Kettering Cancer Center and the Van Andel Institute, have pinpointed a molecular “switch” that energizes sperm for their final sprint to an egg. This discovery could transform infertility treatments and advance safe, nonhormonal…
-
Sperm Metabolism Breakthrough Could Transform Infertility Treatments
Overview: A Molecular Switch Powers Sperm’s Final Sprint Researchers at Michigan State University have identified a molecular “switch” that ramps up sperm energy just before fertilization. This discovery sheds light on how sperm metabolize glucose and other fuels to enable the rapid, high-energy movement needed to reach and fertilize an egg. The work, conducted in…