Tag: Immunology
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Innovent Highlights Broad Biomedicine Pipeline at 2025 ACR Annual Meeting
Innovent Showcases Broad Biomedicine Pipeline at 2025 ACR Annual Meeting Innovent Biologics, a leading biopharmaceutical company focused on developing, manufacturing, and commercializing high-quality medicines, today highlighted multiple research results from its general biomedicine pipeline at the 2025 American College of Rheumatology (ACR) Annual Meeting. The event, held in San Francisco with contributions from Innovent’s teams…
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Hypoxia Reprograms Neutrophils: Long-Term Immune Impact
Hypoxia and the immune system: a surprising link Scientists are uncovering how low oxygen levels, or hypoxia, can do more than cause immediate trouble breathing. New research suggests that hypoxia can reprogram a key group of immune cells—neutrophils—by changing the way their genetic material is packaged. This finding points to a lasting impact on the…
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HIV Research: A Catalyst for Breakthroughs Across Medicine
The Enduring Impact of HIV Research HIV/AIDS research has become more than a focused effort against a single disease. Over the past four decades, U.S.-funded HIV research has advanced science in ways that touch immunology, cancer therapy, vaccines, and global health at large. A recent Nature Medicine commentary by leading researchers highlights how this sustained…
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HIV Research: A Catalyst for Global Medicine and Innovation
Introduction: A Forty-Year Arc of Impact HIV/AIDS research has not only transformed care for people living with HIV but has become a powerful engine of scientific discovery across medicine. In a recent Nature Medicine commentary, leading researchers reflect on four decades of U.S.-funded HIV science and its outsized influence on immunology, cancer therapy, cardiovascular and…
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How HIV/AIDS Research Transformed Global Health: From Immunology to Cancer Therapies and Beyond
HIV Research as a Catalyst for Broad Scientific Advances Four decades of U.S.-funded HIV/AIDS research have done more than extend lives affected by the virus. In a recent Nature Medicine commentary, scientists emphasize that the pursuit of HIV prevention, treatment, and cure has become a powerful engine for understanding human biology and developing therapies for…
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Portlaoise Boy Finds Life-Changing Cure Through Groundbreaking ADA-SCID Gene Therapy
Groundbreaking Gene Therapy Brings New Hope for ADA-SCID Patients A nine-year-old boy from Portlaoise, Ireland, has become one of the most compelling success stories in recent medical research after participating in a landmark gene therapy trial. Andy Cash, diagnosed with adenosine deaminase-deficient severe combined immunodeficiency (ADA-SCID) as a newborn, has seen transformative improvements that his…
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Checkpoint inhibitors reveal tissue repair role, offering hope for chronic wounds
Unveiling a new function for a familiar immune brake Checkpoint inhibitors are well known for their role in cancer therapy, where they release the immune system’s brakes to attack tumor cells. In a surprising twist, researchers from the University of Zurich (UZH) have uncovered a second, equally important function: TIGIT, a checkpoint protein, promotes tissue…
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Checkpoint Inhibitor TIGIT Promotes Tissue Repair
New role for checkpoint inhibitors in tissue healing Checkpoint inhibitors are best known for unleashing the immune system against cancer. A surprising new perspective emerging from researchers at the University of Zurich (UZH) shows that one of these inhibitors, TIGIT, also plays a vital part in tissue repair. Published in Nature Immunology, the study reveals…
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TIGIT: Immune Checkpoint Promoter of Tissue Healing Could Change Fibrosis and Wound Care
Groundbreaking finding: TIGIT helps tissue repair Researchers at the University of Zurich (UZH) have uncovered a surprising role for the immune checkpoint inhibitor TIGIT beyond its well-known function as a cancer therapy target. In a study led by Nicole Joller, the team demonstrated that TIGIT not only helps regulate immune responses during infections but also…
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TIGIT Promotes Tissue Healing: A New Role for Immune Checkpoints
Unlocking a Hidden Role for Immune Checkpoints Immune checkpoint inhibitors are best known as cancer therapies that unleash the body’s defenses against tumors. A team from the University of Zurich (UZH) has uncovered a surprising new function for one of these molecules: TIGIT, a surface receptor on immune cells, also promotes tissue healing after viral…