Tag: Immune tolerance
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Vascular-Associated Fibroblastic Cells: A New Guard for Insulin-Producing Cells in Type 1 Diabetes
Breakthrough Finds VAFs as Pancreatic Peacekeepers In a landmark study published in Cell Reports on September 23, 2025, researchers from Scripps Research have identified a previously unrecognized group of cells that actively shield insulin-producing cells in the pancreas. These vascular-associated fibroblastic cells (VAFs) appear to act as molecular peacekeepers, helping to keep autoimmune attacks at…
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Discovery of vascular-associated fibroblastic cells opens new path for diabetes treatment
New discovery reveals pancreas’s immune tolerance allies Researchers at Scripps Research have identified a previously unrecognized cell type in the pancreas—vascular-associated fibroblastic cells (VAFs)—that appear to actively protect insulin-producing cells from autoimmune attack. Published in Cell Reports on September 23, 2025, the study describes how VAFs help maintain immune tolerance in the pancreas, shedding new…
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Vascular-Associated Fibroblastic Cells Shield Insulin Production, Paving Hopeful Path for Type 1 Diabetes Therapies
Uncovering a Cellular Peacekeeper in the Pancreas Researchers at Scripps Research have identified a novel cell type that actively protects insulin-producing cells from autoimmune attack. The discovery centers on vascular-associated fibroblastic cells (VAFs), which appear to act as molecular peacekeepers within the pancreas. Published in Cell Reports on September 23, 2025, the study offers a…
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Nobel Prize in Medicine Honors Trio Uncovering Immune System’s ‘Security Guards’
Nobel Prize in Medicine Awards Recognize Immune System Regulators The Nobel Prize in Medicine was awarded to a US-Japanese trio for groundbreaking work on how the immune system keeps itself in check. Mary Brunkow and Fred Ramsdell, both based in the United States, and Shimon Sakaguchi of Japan’s Osaka University were celebrated for identifying the…