Tag: IL-15
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Engineered Salmonella therapy delivers immune payloads to combat cancer
Breakthrough in bacterial immunotherapy: ACTM-838 targets solid tumors Solid tumors have long posed a challenge for immunotherapy, often creating an immune-suppressive microenvironment that thwarts even the most advanced treatments. A new study published in Oncotarget (Volume 16, October 6, 2025) introduces ACTM-838, a novel systemically delivered bacterial immunotherapy designed to enrich in solid tumors and…
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Engineered Salmonella Therapy Delivers Immune Payloads to Fight Cancer
New Bacterial Immunotherapy Targets Solid Tumors Researchers have unveiled ACTM-838, a novel, systemically delivered bacterial immunotherapy designed to enrich solid tumors with immune-stimulating payloads. Published in Volume 16 of Oncotarget on October 6, 2025, the study demonstrates how a specially engineered Salmonella Typhimurium strain can safely localize to tumors and deliver potent immune activators directly…