Tag: IL-12
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Engineered CAR T cells show promise against solid tumors
A breakthrough design for solid tumors: CAR T cells deliver IL-12 and PD-L1 blocker Chimeric antigen receptor (CAR) T cell therapy has transformed treatments for certain blood cancers, but solid tumors such as ovarian, prostate, breast, and pancreatic cancers have posed stubborn challenges. A collaborative effort from USC Norris Comprehensive Cancer Center and City of…
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Engineered CAR T Cells Target Solid Tumors with IL-12 PD-L1 Fusion
A new approach targets solid tumors Chimeric antigen receptor (CAR) T cell therapy has transformed the treatment landscape for certain blood cancers, but solid tumors—such as prostate, breast, lung, and ovarian cancers—have remained stubborn hurdles. A collaboration between USC Norris Comprehensive Cancer Center and City of Hope has yielded a promising solution: engineering CAR T…