Tag: high-fat diet


  • Ganoderma lucidum and Liver Health: Protecting the Liver from High-Fat Diet Lipotoxicity

    Ganoderma lucidum and Liver Health: Protecting the Liver from High-Fat Diet Lipotoxicity

    Understanding the Challenge: High-Fat Diets and Liver Health Long-term consumption of high-fat diets (HFD) is known to impose lipotoxic stress on multiple organs, with the liver bearing a heavy burden. As fat accumulates, hepatocytes face metabolic dysfunction, inflammation, and cell injury that can progress to steatosis and liver disease. This emerging research explores not only…

  • Ganoderma lucidum Shields Liver Damage from High-Fat Diets

    Ganoderma lucidum Shields Liver Damage from High-Fat Diets

    Overview: High-Fat Diets, Liver Lipotoxicity, and the Search for Protection Long-term consumption of a high-fat diet (HFD) is linked to progressive liver damage, metabolic dysfunction, and fears of nonalcoholic fatty liver disease. In a recent study, researchers investigated how HFD drives lipid accumulation, inflammatory responses, and cellular stress in the liver, and whether Ganoderma lucidum…

  • Ganoderma lucidum protects the liver from high-fat diet lipotoxicity: new insights

    Ganoderma lucidum protects the liver from high-fat diet lipotoxicity: new insights

    Background: The challenge of high-fat diet lipotoxicity A sustained high-fat diet (HFD) can drive metabolic derangements that disproportionately affect the liver. Lipotoxicity from excess fatty acids and lipid intermediates promotes hepatic steatosis, liver injury, and inflammation, contributing to metabolic diseases such as non-alcoholic fatty liver disease (NAFLD). Understanding the dynamic effects of HFD on liver…