Tag: Hepatocellular carcinoma
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Identification of Novel TERT Promoter Mutations in Chronic Hepatitis B and Their Link to Hepatocellular Carcinoma
Background: Hepatitis B and Liver Cancer Risk Liver cancer remains a major global health challenge, with hepatocellular carcinoma (HCC) being the most common form. Chronic hepatitis B virus (HBV) infection is a well-established driver of HCC, contributing to carcinogenesis through chronic inflammation, liver injury, and genomic instability. In recent years, researchers have turned a spotlight…
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Establishment and Validation of a Prognostic Nomogram Model for Radica: Improving Liver Cancer Outcomes
Introduction Liver cancer remains a leading global health challenge, with hepatocellular carcinoma (HCC) representing the majority of cases. In China and many high-burden regions, HCC is a major cause of cancer-related mortality. Recent research has focused on building robust prognostic tools that can accurately predict patient outcomes and guide individualized treatment decisions. This article summarizes…
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Establishment and Validation of a Prognostic Nomogram Model for Hepatocellular Carcinoma: A Comprehensive Study
Introduction Liver cancer remains a global health challenge, with hepatocellular carcinoma (HCC) representing the majority of cases. In China, HCC is a leading cause of cancer-related mortality, contributing to a substantial portion of the worldwide burden each year. This study focuses on constructing and validating a robust prognostic nomogram to predict overall survival (OS) in…
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Establishment and Validation of a Prognostic Nomogram Model for Radical Resection of Hepatocellular Carcinoma
Background and Purpose Liver cancer, particularly hepatocellular carcinoma (HCC), remains a leading cause of cancer mortality worldwide. In China, HCC accounts for a substantial share of liver cancer cases and deaths each year. Accurate, individualized survival predictions after radical treatment are essential to guide postoperative management, adjuvant therapy decisions, and patient counseling. This article outlines…
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DAA Therapy: Persistent HCC Risk in HIV-HCV Coinfection Explained
Understanding the Context: HIV, HCV, and HCC Hepatitis C virus (HCV) infection and human immunodeficiency virus (HIV) coinfection pose unique health challenges. In the past decade, direct-acting antivirals (DAAs) transformed HCV treatment, offering high cure rates and improved liver outcomes. However, even after what appears to be a sustained virologic response or cure, researchers have…
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DAA Therapy and HCC Risk in HIV-HCV Coinfection: Decline Over Time
Overview: HIV, HCV, and the risk of hepatocellular carcinoma Hepatocellular carcinoma (HCC) remains a major concern for people living with HIV who have a history of hepatitis C virus (HCV) infection. Even after successful HCV cure with direct-acting antivirals (DAAs), researchers have observed that the risk of developing HCC does not disappear entirely. This evolving…
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DAA Therapy Linked to Falling HCC Risk in HIV-HCV Coinfection
Hepatitis C, HIV, and the evolving role of DAAs Direct-acting antivirals (DAAs) have transformed hepatitis C virus (HCV) treatment, offering cure rates that were once unimaginable. For people living with both HIV and HCV, the landscape has been more complex. While DAAs effectively clear the hepatitis C infection, experts have long asked how this virologic…
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Exact Sciences Unveils Breakthrough Blood Test for Early Liver Cancer Detection
Groundbreaking Validation of a Blood-Based Liver Cancer Screening Tool Exact Sciences Corp. has announced pivotal clinical validation results from the ALTUS study, a prospective, head-to-head evaluation designed to assess a blood-based surveillance test for liver cancer. Conducted in a real-world, high-risk population, the ALTUS study (NCT: 05064553) represents a major step toward accessible, non-invasive screening…
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Free, Nurse-Led Support Line Opens for Primary Liver Cancer During Liver Cancer Awareness Month
A New Lifeline for Primary Liver Cancer Patients In a significant move to bolster support for those affected by primary liver cancer, the Liver Foundation has launched a free, nurse-led support line during Liver Cancer Awareness Month. The service is designed to provide expert guidance, compassionate listening, and practical information to patients and their loved…