Tag: HD
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Smoking Tied to Faster Huntington’s Decline: What Clinicians Need to Know
Overview: Smoking as a Modifiable Factor in Huntington’s Disease Huntington’s disease (HD) is a progressive, currently incurable neurodegenerative disorder. While genetics set the stage, modifiable environmental factors may influence when symptoms start and how quickly they advance. A recent analysis using Periodic Dataset 4 from Enroll-HD examined 2,438 individuals, including 799 presymptomatic carriers with four…
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Huntington’s Disease Gene Therapy: Promise Amid Unanswered Questions
New Hope in Huntington’s Disease Gene Therapy A European biotech company, uniQure, has released preliminary results from an experimental gene therapy (AMT-130) aimed at Huntington’s disease. The data suggest the therapy could slow disease progression by about 75% over three years in patients receiving the highest dose. The treatment is delivered directly into the brain…