Tag: GRP78
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ER Stress-Related Biomarkers in COPD: Unlocking New Insights for Diagnosis and Therapy
Understanding ER Stress and COPD Chronic obstructive pulmonary disease (COPD) is a complex, heterogeneous condition marked by persistent inflammation and progressive decline in lung function. Recent research highlights the role of endoplasmic reticulum (ER) stress as a key cellular stress response in COPD. When misfolded proteins accumulate in the ER, a signaling cascade known as…
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ER Stress Biomarkers in COPD: Key Indicators of Disease Activity
Introduction to ER Stress and COPD Chronic obstructive pulmonary disease (COPD) is a heterogeneous respiratory condition marked by persistent inflammation, airway remodeling, and progressive loss of lung function. In recent years, researchers have turned to cellular stress pathways to better understand COPD pathogenesis. A central player is endoplasmic reticulum (ER) stress, a cellular state triggered…