Tag: GPX4
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The Dual Role of SLC7A11 in Colorectal Cancer Ferroptosis: From Molecules to Therapies
Understanding Ferroptosis and SLC7A11 Ferroptosis is a regulated form of cell death driven by iron-dependent lipid peroxidation. In colorectal cancer (CRC), ferroptosis represents a promising avenue to overcome resistance to conventional therapies. Central to this process is SLC7A11, a component of the cystine/glutamate antiporter system Xc–, which imports cystine into cells in exchange for glutamate.…


