Tag: geriatric medicine
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Propofol Combination Anesthesia: Effects on Cognition and Anesthesia Depth
Introduction Propofol is a widely used induction and maintenance agent in modern anesthesia. When combined with other anesthetic drugs, it can offer benefits such as smoother induction, reduced hemodynamic fluctuations, and tailored levels of sedation. This article reviews how propofol combinations affect anesthesia depth and postoperative cognitive function, with particular attention to elderly patients who…
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Non-DNMT3A CHIP Variants Elevate Heart Failure Risk in Older Adults
What is CHIP and why it matters? Clonal hematopoiesis of indeterminate potential (CHIP) describes a mosaic of blood cells that carry somatic mutations, typically acquired with age. While many CHIP mutations are harmless in themselves, certain gene variants are increasingly associated with adverse cardiovascular outcomes. A growing body of research highlights how CHIP can influence…